| 郑际烈,沈伟侠,杨军.雷公藤治疗白塞氏病的临床观察[J].中国中西医结合杂志,1983,(6):346-348,324 |
| 雷公藤治疗白塞氏病的临床观察 |
| Clinical Observation on the Treatment of Behcet’s Disease with Tripterygium wilfordii |
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| DOI： |
| 中文关键词: 雷公藤 白塞氏病 复发性口疮 治疗后 血栓性静脉炎 皮肤血管炎 眼色素层炎 正常值 病因不明 副作用 |
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| 中文摘要: |
| 白塞氏病(Behcet’s Disease,简称 BD)的病因不明,治疗颇为困难。我们于1976年开始应用雷公藤(Tripterygium WilfordiiHook F)治疗47例,取得显著疗效。兹将疗效及免疫功能检测分析如下。临床资料一、病例来源:门诊 BD 患者47例中,女 |
| 英文摘要: |
| 47 cases of Behcet’s diseases(20 males,27 females)were treated by Tripterygium wilfordii Hook.f(TW). Mucocutaneous symptoms and signs were predominant at the time when TW treatment was started.TW is significantly efficacious for 37 patients and efficacious for 10 patients,with a gross efficiency of 100%.The experiences gained have indicated that TW may be the best cure for skin and genital lesions,angiitis,myalgia, arthritis and fever,and help improveeye lesions and recurrent aphthae.Peripheral blood lymphocytes blastogenesis test,and tests concerning E-RFC,Tr cell,serum IgG,saliva SIgA,etc.were investigated in 47 patients.It has been found that the cell mediated immunity deficiency and humeral immunity were increased.The mean percentage(8.76 ±3.03%)of Tr cell found in 47 patients with TW was significantly lower than that(9.85±4.33%)found in pre- treatment(P<0.01).After the treatment by TW,E-RFC increased to the normal leveL TW has the same effect as steroid.Its anti-inflammatory effect is of a non-specific nature,fast and less toxic. |
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