肿瘤脾虚患者运化功能的初步研究

作者	单位
郁仁存	北京中医医院肿瘤科
杨治英	北京中医医院肿瘤科
金静愉	北京中医医院肿瘤科
张绳祖	北京中医研究所免疫研究室
王广才	北京中医医院同位素室
胡玉芳	北京中医医院肿瘤科
金铃	北京中医医院肿瘤科
关天瑜	北京中医医院肿瘤科
饶燮卿	北京中医医院肿瘤科
田兆黎	北京中医医院肿瘤科
高永福	北京中医医院肿瘤科

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中文摘要:

本文报告采用同位素¹³¹碘胶囊示踪法,观察消化道排空运动机能.发现肿瘤脾虚证患者的消化道排空运动速度比肿瘤非脾虚证患者和正常人明显加快,用健脾补气药治疗可以改善;用小剂量阿托品口服可以纠正之,提示其消化道排空运动加快可能主要是由于副交感神经兴奋增强所致。

英文摘要:

With radioisotope tracer,a new method of observing the emptying movemet of human alimentary canal has been worked out.Ten hours after taking a capsule which contains 1-microcuries of ¹³¹I and is not to be destroyed when passing through the alimentary canal,the position of capsule is detected by Hys-401 Type Radioisotope Scanner.19 cases of tumor patients with"Pi Ku"（deficiency in the spleen）and 16 cases of tumor patients without"Pi Xu"and 45 normal subject as control group were observed.The results showed significant difference between tumor patients wih"Pi Xu"and tumor patients without"Pi Xu"and normal subjects.The speed of emptying movemet of the small intestine and colon in patients with"Pi Xu"is,greater than that in patients without"Pi Xu"and normals （P<0.005 and P<0.001）.The emptying movement improved after being treatewith"Jian Pi Bu Qi" （健脾补气,invigorating spleen and strengthening vital energy）drugs.This stuly has proved that the functional disturbance of digestive tract in patients with"Pi Xu"is aused by increase of parasympathetic activity which can be corrected by oral administration of srall dosage of Atropine （0.03mg）.But it has no effect on tumor patients without"Pi Xu". It follows that deficiency in the spleen of TCM has its pathophysiologic bsis.It is"Pi Xu"that brings on the difference in emptying movement of the tumor patients irrespecte of the kind or type of the tumor.

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