| 黄亚坤.对羟福林与N-甲基酪胺治疗休克53例的临床观察[J].中国中西医结合杂志,1984,(2):95-96,67 |
| 对羟福林与N-甲基酪胺治疗休克53例的临床观察 |
| Clinical Observation on Synephrine and N-Methyltyramine in the Treatment of 53 Shock Cases |
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| DOI： |
| 中文关键词: 抗休克 甲基酪胺 药理作用 血管阻力指数 动物实验 副作用 注射液 冠脉流量 合成品 对羟福林 |
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| 中文摘要: |
| 本文报道合成品对羟福林与 N-甲基酪胺治疗休克53例,有效率86.7%。本品质纯用量小,升压明显,无不良副作用,但动物实验提示合成品在增加冠脉流量,减少血管阻力指数方面不如枳实,故认为合成品还不能完全代替枳实。枳实中的其他成分对治疗休克有益的药理作用还值得探讨。 |
| 英文摘要: |
| This article reports the results of the effect-of a synthetic compound(a mixture of synephrine and N-methyltyramine)in 53 shock cases.There are 36 cases(68%)with prominent effect;10 cases(18.7%)with temporary effect and 7 cases(13.7%)in failure.Thus the total effective percentage of the treatment is 86.7%. This kind of medicine is marked by the fact that the blood pressure increased conspicuously,the pulse pressure was great,and the quantity of the urine increased.As compared with the natural preparation(Citrus Aurantium L.),the compound has many features, such as pure in quality;small in dose and without side effects.But animal experiments showed that the synthetic compound was less effective than the natural preparation,especially with respect to the increase of coronary blood flow volume and the decrease of vessel resistance index.Thus.it is suggested that the artificial compound cannot entirely replace the natural preparation.The other benificial action of the natural preparation to the shock cases is worth further investigating. |
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