从尿中肌酐、尿素、钾、磷、镁的排泄量探讨慢性肾炎患者阴虚、阳虚的病理基础

作者	单位
毛良	上海中医学院中医实验研究室
丁伟璜	上海中医学院中医实验研究室
宋菊敏	上海中医学院中医实验研究室

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中文摘要:

本文从营养学的角度探讨慢性肾炎患者阴虚和阳虚的病理生化学基础。慢性肾炎患者在相同的 Ccr 和尿素排泄量时,其肌酐系数以阳虚者明显低于阴虚者。肌酐、尿素、钾、磷、镁的排泄量也以阳虚者明显低于正常人和阴虚者。提示本病阳虚系机体营养不良和能量代谢降低,而阴虚系机体营养状况一般或偏低,而能量代谢则有所增加。

英文摘要:

Based on the current thcories of nutrition and metabolism,the contents of urinary creatinine(Cr),urea(Ur), potassium(K),inorganic phosphorus(P)and magnesium(Mg)of Yang-deficiency anct Yin-deficiency patients with chronic nephritis were compared.Results showed that contents of urinary Cr,Ur,K,P and Mg of the Yang- deficiency patients were significantly lower than those of the Yin-deficiency patients and normal.The contents of urinary K,P and Mg of the Yin-deficiency patients were normal,the urinary Ur was subnormal,but the urinary Cr was higher than normal.In addition,the content of urinary Cr showed an evident positive correlation with the creatinine clearance(Ccr)and urinary Ur.With the same value of Ccr or urinary Ur,the content of urinary Crin the Yang-deficiency patients was markedly lower than that in the Yin-deficiency patients.These findings suggested that the pathobiochemical basis of Yang-deficiency and Yin-deficiency may be explained as a morbid condition caused by disorders of nutrition and metabolism of the body.Yang-deficiency is a syndrome in patients with malnutrition and low metabolism,while Yin-deficiency is a syndrome in patients with normal or subnormal nutrition and high metabolism.

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