| 王庆文,井枫林,李秀兰,李莹,李龙云,叶金梅,孟玉珍,李淑子,孙景方.痰喘净药理实验与治疗慢性支气管炎300例疗效观察[J].中国中西医结合杂志,1984,(4):222-223,197 |
| 痰喘净药理实验与治疗慢性支气管炎300例疗效观察 |
| The Treatment of Chronic Bronchitis with Tan Chuan Jing——A Clinical Study of 300 Cases and Pharmacological Experiment |
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| DOI： |
| 中文关键词: 慢性支气管炎 药理实验 临床疗效观察 平喘作用 黄柏果 消炎作用 喘息型 挥发油 酚红法 小鼠 |
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| 中文摘要: |
| 本文报告了痰喘净治疗慢性支气管炎的药理实验和临床观察结果。药理实验采用小鼠酚红法、豚鼠组织胺引喘法、小鼠氨雾法分别进行观察,结果表明有明显的社痰平喘作用。临床疗效观察在东北地区12～1月份进行,农村与城市二组结果均显示了明显的祛痰、平喘和消炎作用,其中喘息型疗效高于单纯型。 |
| 英文摘要: |
| Tan CChuan Jing is a preparation consisting of volatile oil of Fructus Phellodendron amurense（黄柏果）and extract of Sopliora flavescens（苦参）. Phenol red tests revealed marked expectorant action of Tan Chuan Jing in mice.In guinea pig,the preparation showed evident spasmolytic action on tracheal spasm induced by histamin in vivo.but no antitussive effect was observed.LD50of the preparation was 2.969±0.172g/kg for mice;subacute toxicity tests showed that Tan Chuan Jing（po.1100mg/kg）delayed the growing of rats,but exerted no influence on routine blood test,CPT and BUN. 300 patients were treated with Tan Chuan Jing,each taking 2 capsules,two times a day during the coldest season.The patients treated with this preparation had a total effective rate of 97% with a prominent improvement rate of 65.%.Tan Chuan Jing has marked expectorant,antiasthmatic and antiphlogistic effects,however,it has little antitussive effect.This preparation is applicable to both types of chronic bronchitis,simple and asthmatic,but it is more effective in treating the latter.Clinically,it showed no apparent toxic side effect. |
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