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Pregnancy Toxemia,Research Group,of.中药止抽散综合方案治疗先兆子痫100例初步观察和药理研究[J].中国中西医结合杂志,1984,(8):472-475,451
中药止抽散综合方案治疗先兆子痫100例初步观察和药理研究
"Zhi Chou San"(Anticonvulsive Powder)in the Treatment of Preeclampsia——A Report of 100 Cases
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中文关键词:  综合方案  初步观察  药理研究  妊娠中毒症  产后大出血  胎婴儿  中药  自觉症状  先兆子痫  治疗方案
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Pregnancy Toxemia,Research Group,of 湖北中医学院附属医院妇产科妊毒组
湖北中医学院附属医院中草药研究室 
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中文摘要:
      本文报告用中药止抽散综合方案治疗先兆子痫100例,结果血压、水肿、蛋白尿及自觉症状明显改善,滞产和产后大出血明显下降,胎婴儿无死亡,新生儿窒息率降低。药理实验证明该药有镇静、降压作用,一其结果与临床观察一致。
英文摘要:
      From March 1979 to March 1983,100 cases of Preeclampsia were treated with"Zhi Chou San" in our hospital,the results were as follows:(1)An average drop of blood pressure:systolic 13.66 mmHg,diastolic 4.3 mmHg was observed.Marked improvement was also found in oedema,proteinuria and general condition of the patient.(2)Incidence of prolonged labour and pastpartum uterine bleeding reduced greatly in comparison with that of the group treated with western medicine,P<0.01.(3)There was no mortality of fetus or newborn in the group treated with"Zhi Chou San";The rate of fetal asphyxia was 20.21%,while that of the group treated with western medicine was as high as 39.16%. Four cases of asphyxia of the newborn were observed,which also showed marked decrease in comparison with the group treated with western medicine,P<0.01. Pharmacological tests:Intraperitoneal injection or oral administration of"Zhi Chou San"to the mice caused obvious drop of blood pressure and sedation,a result similar to that observed in human in clinical practice.Oral administration of"Zhi Chou San"to mice with a dosage of 15g/kg each time would cause neither death nor harm.
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