利胆、理气中药和针刺日月、期门穴对人Oddi氏括约肌的影响

胆汁的排泄和胆总管结石的排出受多种因素的影响,其中 Oddi 氏括约肌的机能状态是一个重要因素。本文报告利用胆道灌注测压和胆道录象等手段,从机能和形态的两个角度观察、分析了临床常用的利胆、理气中药和针刺右日月、期门穴对人 Oddi 氏括约肌运动的影响。实验结果提示,利胆、理气药都能松弛括约肌,降低胆压,且后者作用大于前者。针刺右日月,期门穴对正常人的 Oddi 氏括约肌的运动及胆总管压力无明显影响。

英文摘要:

The discharge of the choledochal stones is affected by many factors.Among them the function and condition of Oddi’s sphincter are the most important.Biliary manometry and cinecholangiography were employed to investigate the therapeutic mechanism of some medicinal herbs and acupuncture.The results of the study suggested that administration of choleretic and energy-regulating herbs could relax the sphincter and reduce the pressure of the biliary tract.The latter effect was even more obvious than the former.Sixty minutes after administration of the choleretic the choledochal pressure was reduced by 12.6 percent (P<0.05).Thirty minutes after administration of the herbs regulating vital energy the pressure was found to drop markedly and reach 27.7%(P<0.01)the lowest level in 90 minutes.The pressure began to rise to its normal level in 120 minutes.Sixty minutes after administration of choleretics both the relaxing and contracting cycle and the relaxing period of the sphincter were prolonged(P<0.05).Thirty and Sixty minutes after administration of energy-regulating herbs the cycle and relaxing period were also obviously prolonged (P<0.01).The movements of Oddi’s sphincter and the choledochai pressure were not influenced by needling the points Riyue and Qimen.Based on the results of the study,the clinical use of choleretic and energy- regulating herbs and acupuncture was discussed.

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