脾虚证慢性胃病患者胃粘膜与血浆cAMP和cGMP测定及其临床意义

Measurement ef Gastric Mucosa and Plasma cAMP and cGMP in Patients with Chronic Gastric Diseases Due to Spleen Deficiency and Its Clinical Significance

免费下载全文查看/发表评论下载PDF阅读器

DOI：

中文关键词: 胃粘膜细胞脾虚证脾气虚证脾虚气滞证血浆环核苷酸胃病患者显著差异测定慢性胃炎肠化生

英文关键词:

基金项目:

作者	单位
尹光耀	无锡市第三医院
周奚中	无锡市第三医院
唐静芬	无锡市第三医院
马荣赓	无锡市第三医院
何立璋	无锡市第三医院
杨柏岩	无锡市第三医院
汪朋梅	无锡市第三医院
许文琴	无锡市第三医院
俞宪民	无锡市第三医院
沈亚英	江苏省原子医学研究所
吴佳平	江苏省原子医学研究所

摘要点击次数: 1928

全文下载次数: 996

中文摘要:

通过测定21例脾虚证慢性胃病患者胃粘膜及血浆环核苷酸含量,发现胃粘膜与血浆 cAMP 在脾气虚证和脾虚气滞证间有显著差异;cAMP 在胃粘膜的正常组织与病灶组织间、正常人与脾虚证病人的血浆间均有显著的量变。因此认为环核苷酸的含量可反映脾虚证的部分本质,测定其含量有助于临床上判断病情和疗效。

英文摘要:

Gastric mueosa and plasma cAMP and cGMP level were detected in 21 cases of chronic gastric diseases with spleen deficiency.The cAMP and cGMP level in normal gastric mucosa of patients with spleen deficiency was higher than that in focal gastric mucosa,P<0.01—0.001;the cAMP level in normal gastric mucosa of patients with deficiency of spleen-energy(脾气虚)and spleen deficiency with energy stagnation(脾虚气滞)was higher than that in focal gastric mucosa,statistical differences being also significant,P<0.05—0.01.However,no marked changes of cGMP level were observed.Marked differences in cAMP mean level of the normal and focal gastric mucosa were also observed between cases with dificiency of spleen-energy and cases with spleen deficiency and energy stagnation,P<0.01.The statistical differences in plasma cAMP level were also found between normal subjects and spleen deficiency patients,including deficiency of spleen-energy and spleen deficiency with energy stagnation,P <0.001.However,no marked alterations of plasma cGMP level were found,All these findings suggest that cAMP level is closely related to the syndrome of deficiency in the spleen and the determination of cAMP level might be of clinical significance in estimating the course of the disease and therapeutic efficacy.

关闭