冬虫夏草及人工培养菌丝体对小鼠内脏单核—巨噬细胞系统免疫功能影响的研究

A Study on the Influences of Natural Cordyceps Sinensis and Its Cultured Mycelia on Murine lmmuno-Organs and Functions of Mononuclear Phagocyte System

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DOI：

中文关键词: 冬虫夏草人工培养菌丝体脾巨噬细胞功能影响小鼠艾氏腹水癌显著差异制剂保护试验吞噬功能人工菌丝

英文关键词:

基金项目:

作者	单位
陈道明	海军医学研究所
张淑兰	海军医学研究所
李政年	海军医学研究所
程振球	海军医学研究所
刘晓平	海军医学研究所

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中文摘要:

本实验用免疫组织学方法表明天然冬虫夏草(Cordyceps sinensis)及人工培养菌丝体制剂对小鼠免疫器官具有明显影响,可使肝、脾增大,胸腺缩小,能使 Kupffer细胞吞噬功能增强,并使脾巨噬细胞增殖,证实其对单核—巨噬细胞系统功能有激活作用,而天然与人工菌丝体制剂组问互比,无显著差异,提示两者作用基本一致,为临床应用提供实验依据。

英文摘要:

By means of immunological methods,we found that the natural Cordyceps sinensis and its cultured mycelia have significant effect on the immuno-organs of mice,such as splenomegaly,liver enlargement and the shrinkage of thymus.Under the light microscope we also observed that the Kupffer’s cells and the phagocytes increased in the spleen.All these findings suggest that the functions of mononuclear phagocyte system are activated by these drugs.But there is no significant difference between natural Cordyeeps sinensis and its cultured mycelia in their action(P<0.05).The pharmacological functions of both are similar.The experimental results may throw some light on their clinical application.

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