张淑兰,陈道明,程振球,刘晓平.冬虫夏草及其人工菌丝对小鼠腹腔巨噬细胞激活作用的实验观察[J].中国中西医结合杂志,1985,(1):45-47,5 |
冬虫夏草及其人工菌丝对小鼠腹腔巨噬细胞激活作用的实验观察 |
Activation of Murine Peritoneal Macrophage by the Natural Cordyceps sinensis and Its Cultured Mycelia |
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中文关键词: 冬虫夏草 人工菌丝 吞噬百分率 天然虫草 激活作用 水提物 吞噬指数 小鼠腹腔巨噬细胞 酸性磷酸酶活性 腹腔液 |
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中文摘要: |
本文报告冬虫夏草及其人工菌丝水提物对小鼠腹腔巨噬细胞(Mφ)激活作用的实验观察。结果表明,每天肌注5g/kg,连续4天,能使 Mφ的吞噬百分率和吞噬指数明显增加,与对照组相比,P<0.001,而天然虫草与人工菌丝之间则无明显差异。还证明Mφ内酸性磷酸酶活性也明显增强。提示人工菌丝具有与天然虫草类似的效应,另外对该药激活 Mφ的机理还进行了初步探讨。 |
英文摘要: |
Natural Cordyceps sinensis and cultured mycelia were given to experimental mice intramuscularly in dose of 5g/kg per day tor 4 days.Results showed that phagocytic index and percentage of phagocytosis of the murine peritoneal macrophages(PM)increased markedly as compared with controls(P<0.001). But there were no significant differences between natural Cordyceps sinensis and its cultured mycelia. The activity of the acid phosphatase in activated PM was also elevated(P<0.01).All these results suggest that the natural Cordyceps sinensis and its cultured mycelia have similar effects. |
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