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陈思源,李仁康,洪淑云,刘德元,刘建国,邓道济,徐延初,张爱芬,黄鹏飞.雷公藤降尿蛋白的疗效分析——中西医结合治疗肾病综合征30例报告[J].中国中西医结合杂志,1985,(3):164-166,132
雷公藤降尿蛋白的疗效分析——中西医结合治疗肾病综合征30例报告
The Effect of Tripterygium Wilfontii on the Remission of AIbnminuria in Patients with Nephrotic Syndrome
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中文关键词:  雷公藤制剂  尿蛋白  肾病综合征  中西医结合治疗  疗效分析  肾小球疾病  中医辨证论治  主要表现  辨病治疗  强的松
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作者单位
陈思源 武汉医学院第一附属医院中医科 
李仁康 武汉医学院第一附属医院中医科 
洪淑云 武汉医学院第一附属医院中医科 
刘德元 武汉医学院第一附属医院中医科 
刘建国 武汉医学院第一附属医院中医科 
邓道济 武汉医学院第一附属医院药剂科 
徐延初 武汉医学院第一附属医院药剂科 
张爱芬 武汉医学院第一附属医院药剂科 
黄鹏飞 武汉医学院第一附属医院药剂科 
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中文摘要:
      本文着重对雷公藤(Tripterygium wilfordii Hook.f.)降尿蛋白方面的效果作了分组比较。认为雷公藤有效制剂能较快的降尿蛋白,有利于早期改善病变。肾病综合征等肾小球疾病,以蛋白尿为主要表现者,肾功能正常期或"代偿期",在辨病治疗上可首选雷公藤提高疗效、缩短疗程。
英文摘要:
      Thirty-seven cases with primary nephrotic syndrome treated with TCM-WM are reported,with emphasis on the effect of Tripterygium wilfordii on the remission of albuminuria.Shortly after the treatment with Tripterygium wilfordii,marked effect was observed in 5 of 10 cases of primary glomerulonephropathy,and moderate effect in the remaining 5 cases.Of the 20 cases of chronic glomerulonephritis,7 showed significant effect,12 showed moderate effect,only 1 case failed. The average number of days needed for complete remission of albuminuria was 12.45±4.74(mean±SD)in 11 of 25 cases of the 1st group(treated with Tripterygium wilfordii);10.63±3.24 in 8 of 12 cases of the 2nd group(treated with Tripterygium wilfordii and prednisone)and 17.43±8.48 in 7 of 13 cases of the 3rd group(treated with prednisone exclusively).Albuminuria in the 1st and 2nd group disappeared more rapidly than in the 3rd group(P<0.02).No significant difference was found between the 1st and the 2nd group.It is suggested that preparations of Triptervgium wilfordii be used as substitute of corticosteroids.
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