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徐正福,毛月丽,杨有仪,尤银珍,屠伯言,陈湘君,苏励,吴圣农,张永祥.风湿病虚证与全血某些微量元素含量变化关系的初步观察[J].中国中西医结合杂志,1985,(4):229-231,196
风湿病虚证与全血某些微量元素含量变化关系的初步观察
A Preliminary Observation on the Relationship Between Asthenia-Syndrome of Rheumatism and Levels of Some Blood Trace Elements
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DOI:
中文关键词:  风湿病  初步观察  微量元素含量  虚证  阴虚  客观依据  正常人  阳虚  全血微量元素  正常对照组
英文关键词:
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作者单位
徐正福 上海市第八届西学中研究班 
毛月丽 上海市第八届西学中研究班 
杨有仪 上海中医学院 
尤银珍 上海中医学院 
屠伯言 上海市龙华医院 
陈湘君 上海市龙华医院 
苏励 上海市龙华医院 
吴圣农 上海市龙华医院 
张永祥 上海市龙华医院 
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中文摘要:
      本文测定正常人对照纽35例,风湿病43例的全血微量元素 Zn、Cu、Zn/Cu、Pb、Cd 值。风湿病阴虚患者血 Zn 降低,Cu 升高,Zn/Cu 比值下降;阳虚患者相反。分析表明这些变化能作为风湿病虚证辨证的良好客观依据。Pb 值在各组之间均无明显差异,Cd在各组中均未检出。
英文摘要:
      This article reports that blood trace elements(Zn,Cu,Zn/Cu,Pb,Cd)were determined by SVA-1 type oscillographic volampere apparatus in 35 normal subjects for control and 43 patients with rheumatism(26 Yin- deficiency type and 17 Yang-deficiency type). The values in the normal controls were as follows: Zn 255.0±83.5μg/dl,Cu 160.0±42.7μg/dl,Zn/Cu 1.6±0.5, Pb 34.3±22.7μg/dl,but Cd was imponderable in this experiment.The Zn and Zn/Cu values in the patients of the Yin-deficiency group were lower and the Cu value was higher than those in the controls.The values were statistically significant(P<0.001). The Zn value and the Zn/Cu value were strikingly higher(P<0.001)and the Cu value was lower(P<0.05)in the Yang-deficiency rheumatism than those in the controls.The Pb value varied with no statistical significance in all groups(P>0.05).The values of Zn,Cu and Zn/Cu in the Yin-deficiency group differed significantly from those in the Yang-deficiency group.The results indicate that changes in the values of the blood Zn,Ca and Zn/Cu,may be used as an index of the differentiation of asthenia-syndrome of rheumatism. The biochemical mechanism of the blood trace elements Zn,Cu,Zn/Cu suggests that their levels are associated with the hypothalamus-pituitary-adrenal axis as well as sex hormones in patients of both Yin-deficiency and Yang- deficiency types,which is a reaction to the complicated variations of the body.
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