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王贵喜,侯灿.电针“足三里”对大鼠胰腺外分泌功能的影响[J].中国中西医结合杂志,1985,(8):489-492,453
电针“足三里”对大鼠胰腺外分泌功能的影响
Effect of Electroncupuncture of "Zusanli" Point on Exocrine Secretion of Pancreas in Rats
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DOI:
中文关键词:  胰腺外分泌功能  急性胰腺炎  电针  足三里  蛋白浓度  清醒大鼠  针刺治疗  胰液  基础期  麻醉期
英文关键词:
基金项目:
作者单位
王贵喜 广东中山医学院病理生理教研室 
侯灿 广东中山医学院病理生理教研室 
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中文摘要:
      通过慢性胰瘘模型,观察了电针"足三里"对大鼠胰腺外分泌功能的影响,发现电针"足三里"能明显降低大鼠胰液蛋白浓度及其排出量,即抑制了胰酶的分泌。作者认为电针"足三里"的这种(保护胰腺)作用,可能与针刺治疗急性胰腺炎的作用机理有关。
英文摘要:
      Exocrine secretion of pancreas in response to electroacupuncture of"Zusanli"point was observed in conscious and anesthetized rats.Pancreatic juice was collected and studied 3 days after the pancreatic fistula was prepared. Electroacupuncture induced a decrease of protein concentration and output of pancreatic juice in conscious rats,which were still signifincantly below the basal value 120 rain after the end of stimulation;during the acupuncture and 60 min after the end of stimulation,protein concentration and output in the anesthetized rats decreased significantly.These show that electroacupuncturc could inhibit protein secretion in both conscious and anesthetized rats. As to the secretion of water and HCO3-,electroacupuncture brought about a decrease in conscious rats,which lasted 60 min after the end of stimulation,but no inhibition was found in anesthetized rats.This shows that anesthesia under this condition of the experiment could block the inhibiting effect of electroacupuncture on the secretion of water and HCO3- in the rats. The authors hold that mechanism of acupuncture in treating acute pancreatitis may be somewhat related to the inhibiting effect on protein(enzyme)secretion of pancreas mentioned above.
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