生胃宁素片治疗消化性溃疡疗效观察——附199例对照分析

作者	单位
张万岱	第一军医大学南方医院消化内科
续正慧	第一军医大学南方医院消化内科
施长泰	第一军医大学南方医院消化内科
方国存	第一军医大学南方医院消化内科
樊素勤	第一军医大学南方医院消化内科

摘要点击次数: 1590

全文下载次数: 987

中文摘要:

本文报告中西医结合制剂生胃宁素片治疗消化性溃疡88例,中医辨证分型治疗51例,西药生胃酮治疗60例。其平均治疗天数、治愈率、五年复发率分别为30.3天、80.68%,34.09%;39.6天、54.9%、56.52%;32.3天、68.3%、60%。前者较后两者治疗时间短、治愈率高、复发率低并具有统计学意义(P 均<0.01)。动物实验也证实了临床疗效。说明中西医结合治疗消化性溃疡较单独应用中药或西药具有显著优越性。

英文摘要:

The present study includes an analysis of 199 cases of peptic ulcer which were divided into 3 groups:88 cases treated with Sheng Wei Ning tablets,51 cases treated according to TCM typing and 60 cases treated with carbenoxolone.The clinical findings of these 3 groups were quite similar,hence they were comparable.All patients were examined with stomach fibers endoscope both before and after every course of treatment.The mean duration of treatment,percentage of cure and percentage of recurrence within 5 years were 30.3 days,80.68% and 34.09% respectively in the first group;39.6 days, 54.9% and 56.52% in the second group;and 32.2 days,68.3% and 60% in the third group. The first group showed shorter duration of treatment,higher cure rate and lower recurrence rate,and all their differences are statistically significant(P<0.01).Animal experimentation confirmed also that the therapeutic effects on experimental gastric ulcer in rats had similar results.Sheng Wei Ning tablet contains both carbenoxolone and furazolidone;however,its side effects were only 5.6% as compared with 33.3-45.6% of the two latter drugs when used separately.The data reveals that treatment of peptic ulcer with TCM-WM has great advantage over treatment with TCM or WM separately.

关闭