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邵耕,尤肇俊,过鑫昌,王锡田,朱道程,王受益,廖世忠,史晓真,黄竞人.人工虫草治疗高脂血症临床报告[J].中国中西医结合杂志,1985,(11):652-654,642
人工虫草治疗高脂血症临床报告
Treatment of Hyperlipidemia with Cultivated Cordyceps—A Double Blind,Randomized Placebo Control Trial
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DOI:
中文关键词:  人工虫草  高脂血症  高密度脂蛋白胆固醇  总有效率  副作用  治疗后  安慰剂对照  高胆固醇血症  动脉粥样硬化  显著性
英文关键词:
基金项目:
作者单位
邵耕 北京医科大学一附院 
尤肇俊 南京医学院一附院 
过鑫昌 上海瑞金医院 
王锡田 浙江医科大学一附院 
朱道程 苏州医学院一附院 
王受益 上海华山医院 
廖世忠 江西医学院二附院 
史晓真 南昌中西医结合医院 
黄竞人 南昌市三院 
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中文摘要:
      本文报告用双盲随机安慰剂对照方法观察人工虫草治疗高脂血症273例的疗效,结果总胆固醇平均下降17.5%(P<0.001),总有效率61.2%(P<0.005)。甘油三酯平均下降9.93%(P<0.05),总有效率56.7%(P<0.001)。高密度脂蛋白胆固醇上升27.19%(P<0.05),总有效率76.2%(P>0.05)。未发现严重副作用。
英文摘要:
      Cultivated Cordyceps is the cultivated product of strain Cs 4 isolated from Cordyceps Sinensis.Its therapeutic effects on hyperlipidemia were studied by double blind,randomized placebo control trial.Two hundred and seventy-three cases of primary hyperlipidemia were studied.The duration of observation was one to two months. Total cholesterol(TC)blood level was lowered by 17.5% after two months treatment(P<0.001),the percentage of patients who had their TC blood level lowered≥10% as compared with that in the pretreatment stage was 61.2%(P <0.005).Triglyceride(TG)blood level was lowered by 9.9% after one month treatment(P<0.005).The percentage of patients who had their TG blood level lowered≥20% as compared with that in the pretreatment stage was 56.7% (P<0.001).HDL-C blood level was increased by 27.2% after two months treatment.The percentage of patients who had their HDL-C blood level increased≥10% as compared with that in the pretreatment stage was 76.2%(P<0.05). No serious side effect was observed.
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