原发性高血压不同中医分型患者的病理生理变化

A Study on Pathophysiologic Changes in Different Types of Patients with Essential Hypertension Based on Traditional Chinese Medical Classification

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中文关键词: 中医分型原发性高血压气阴两虚型肝肾阴虚型舌质阴虚阳亢型病理生理速尿辨证分型均值

英文关键词:

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作者	单位
王宪衍	上海市高血压研究所
钱文琪	上海市高血压研究所
王孝铭	上海市高血压研究所

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中文摘要:

本文对87例原发性高血压患者进行中医辨证分型,对肌注速尿后的降压及利尿效应进行观察,并测定了血浆 ATⅡ及 PRA 浓度。结果显示:(1)激发 PRA 均值阴虚阳亢型明显低于阴虚型,而气阴两虚型又明显低于阴虚型及肝肾阴虚型+阴虚型。(2)激发 PRA均值舌质淡胖组明显高于舌质红或偏红组。(3)肌注速尿后血压下降幅度舌质红组最大,舌质淡胖组最小。2小时尿量阴虚阳亢组最少,舌质淡胖组最多。从而作者认为不同中医分型的患者存在不同的病理生理特点。这些特点可作为辨证分型时的客观指标和治疗上的参考。

英文摘要:

87 patients with essential hypertension of different types based on TCM classification were studied.The patients’ responses to frusemide injection,including hypotensive effect and diuresis,and some biochemical parameters were observed.The results showed:(1)The mean value of PRA(under renin release stimulation)was found the lowest in patients of Qi Yin Liang Xu(气阴两虚,Deficiency in both Qi and Yin)type and the highest in patients of Yin Xu(阴虚,Deficiency of Yin)type.(2)The mean value of PRA(under renin release stimulation)in patients with pale plump tongue was found significantly higher than that in patients with red or reddish tongue.(3) The antihypertensive effect after frusemide injection in patients with red tongue was found greater in comparison with that observed in patients with pale plump tongue.(4)Diuresis response to frusemide injection was found more significant in patients with pale plump tongue than with red or reddish tongue,and diuresis response was found the least in patients of Yin Xu Yang Kang(阴虚阳亢,Exuberance of Yang due to deficiency of Yin)type. According to above findings we believe that there are some pathophysiologic characteristics in hypertensive patients of different types based on TCM classification,which may be of use in typing and treating their illness.

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