河车大造丸对小鼠粒系祖细胞的影响

作者	单位
庄杰盾	中医研究院西苑医院血液病研究室
廖军鲜	中医研究院西苑医院血液病研究室
谢仁敷	中医研究院西苑医院血液病研究室
周霭祥	中医研究院西苑医院血液病研究室

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中文摘要:

本文为探索河车大造丸的益肾补血作用,采用造血干细胞的培养技术,观察该药对供体小鼠粒系祖细胞(CFU-C CFU-D)的影响,同时测定该药对受体小鼠 CFU-D的作用,并以生理盐水作对照,结合中医理论略加讨论。

英文摘要:

Aplastic anemia patients,were generally treated with prescriptions or herbs which have effects to replenish the vital energy and essence of Kidney,i,e,"Bu Shen"(补肾,tonify the kidney).He Che Da Zao Wan(HCDZW)is one of the prescription commonly used.In order to see how aplastic anemia patients have a good response to Bu Shen herbs,HCDZW was injected hypodermically to a group of mice.Normal saline was given to another group of mice as control,The bone marrow granulocytic pregenitor cells or CFU-D of the experimental group assayed by the diffusion chamber technique,were significantly greater than those of the control(P<0.01).HCDZW does affect CFU-D through some humoral factors.This observation throws light on TCM theory:"Bu Shen"promotes hemopoiesis.

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