中药降脂灵治疗高脂血症100例临床观察

作者	单位
静文英	内蒙古中蒙医院
富贵恩	内蒙古中蒙医院
陈亦玑	内蒙古中蒙医院
席殿文	内蒙古中蒙医院
丁淑英	内蒙古中蒙医院

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中文摘要:

本文报道应用降脂灵冲剂治疗高脂血症100例,并与烟酸肌醇酯组26例及脉通丸组30例对照观察。结果:降脂灵对各种高脂血症均有显著疗效(P<0.001);各组治疗后降血脂有效例数以降脂灵为最多(P<0.05)。本文从中医学角度探讨高脂血症的发病机制,讨论中药降脂灵的药化分析及降血脂机理。

英文摘要:

One hundred patients with hyperlipoidemia were treated with the traditional Chinese drug Jiangzhilin granule. Its effect was compared with 26 patients treated with inositol nicotinate tablets and 30 patients treated with Maitong pills.Jiangzhilin granule was made from Herba Artemisiae,black Gardenia jasminoides,Psoralea corylifolia, Phellodendron amuranse,etc.,and was administered 2.5g thrice daily,the treating course was one month.The patients’ blood lipids were examined and compared before and after treatment. The result shows:(1)Jiangzhilin has significant effect in lowering the increase in blood cholesterol,β- cholesterol,β-lipoprotein and triglyceride(P<0.001),while inositol nicotinate is also effective on β-cholesterol and β-lipoprotein(P<0.05),but it is not so good as Jiangzhilin,and Maitong has the poorest effect on blood lipids.(2) The lowering of these three lipids is most potent in Jiangzhilin group(66～74%),and less effective in the other two groups(38.8～57.7%),with significant difference between them(P<0.05). Hyperlipoidemia may be interpreted as the stagnation of Phlegm in the traditional Chinese medicine.Its treatment should replenish the Liver and Kidney,invigorate the Spleen and relieve the dyspepsia,clear away Heat and promote choleresis,deprive the Dampness and eliminate Phlegm.Based on these principles,Jiangzhilin was formulated.It contains Herba Artemisiae dialkyne ketone,gardenin,pinnatifidic acid,lipolytie ferment,linoleic acid,etc.They all exert favourable effect for lowering blood lipids,and it is cheap in price,with negligible side-effect. It deserves spread for extensive application.(Original article on page 21)

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