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朱伯卿,戴瑞鸿,查娟娟,吕国庆,王受益,孙贻平,范维琥,高肇基,陈熊,蒋丽瑾,徐稚民,孙瑰丽.气血相关理论的研究补气药治疗气虚血瘀型心力衰竭[J].中国中西医结合杂志,1986,(2):75-78,66
气血相关理论的研究补气药治疗气虚血瘀型心力衰竭
Research on Theory of Correlation Between Energy and Blood The Use of Energy-Nourishing Herbs in Treating Patients with Heart Failure of Energy Deficiency and Blood Stasis Type
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DOI:
中文关键词:  心力衰竭  血液流变学指标  补气药  心功能分级  血小板聚集功能  气囊漂浮导管  心脏收缩时间间期  治疗后  相关理论  注射液
英文关键词:
基金项目:
作者单位
朱伯卿 上海医科大学华山医院内科教研室
中西医结合研究所心血管病研究室 
戴瑞鸿 上海医科大学华山医院内科教研室
中西医结合研究所心血管病研究室 
查娟娟 上海医科大学华山医院内科教研室
中西医结合研究所心血管病研究室 
吕国庆 上海医科大学华山医院内科教研室
中西医结合研究所心血管病研究室 
王受益 上海医科大学华山医院内科教研室
中西医结合研究所心血管病研究室 
孙贻平 上海医科大学华山医院内科教研室
中西医结合研究所心血管病研究室 
范维琥 上海医科大学华山医院内科教研室
中西医结合研究所心血管病研究室 
高肇基 上海市中医研究院 
陈熊 上海市中医研究院 
蒋丽瑾 上海市浦东中心医院中西医结合病室 
徐稚民 上海市浦东中心医院中西医结合病室 
孙瑰丽 上海市浦东中心医院中西医结合病室 
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中文摘要:
      39例气虚血瘀型心力衰竭患者通过气囊漂浮导管监测心脏血流动力学及心脏收缩时间间期、血液流变学指标、血小板聚集性等测定,证实补气药党参、黄芪注射液及汤剂均能明显改善心功能,同时使异常的血液流变学指标亦有改善。提示补气药能通过补气强心后达到活血化瘀的作用,从一个侧面论证了气血相关的重要理论。
英文摘要:
      Thirty nine patients with heart failure of energy deficiency and blood stasis type were divided into two groups:Group A consisted of 26 cases,treated with intravenous injection of Astragalus and Codonopsis;group B consisted of 13 cases,treated with decoction of Astragalus and Codonopsis for 2~4 weeks. Eight cases of group A underwent cardiac hemodynamic monitoring for 72 hours by insertion of Swan-Ganz’s catheter.Cardiac output,stroke volume,cardiac index and stroke index showed significant increase after injection of Astragalus and/or Codonopsis(P<0.05~0.01).But pulmonary wedge pressure,pulmonary artery pressure and heart rate did not change significantly(P>0.05). Both groups showed that the value of PEP/LVET somewhat decreased after therapy.Degrees of severity of clinical cardiac performance and energy deficiency and blood stasis were improved correspondingly.Besides,abnormal parametrers of hemorrheology in the two groups were also improved, with blood viscosity and RBC electrophoresis decreasing especially.The platelet aggregation was slightly inhibited.It is indicated that energy-nourishing herbs can activate blood circulation and remove stasis through cardiotonic effect and improvement of cardiac performance.
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