| 廖福龙,黄深,李文,朱惠荣,温瑞兴,韩秀娟.活血化瘀药物药性的血液流变学研究[J].中国中西医结合杂志,1986,(2):103-105,69 |
| 活血化瘀药物药性的血液流变学研究 |
| Hemorheologic Investigation on the Properties of Medicinal Herbs of Promoting Blood Circulation and Removing Stasis |
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| 中文关键词: 血液流变学指标 血液粘度 红细胞聚集指数 切变率 药性 活血药 活血化瘀药 血小板聚集 红细胞比容 血浆粘度 |
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| 中文摘要: |
| 传统的活血化瘀药物,按药性有和血、活血及破血之分类,选用代表药物十味,按15g/kg 的剂量给 Wistar 大鼠口服4日(对照组给水)。采用 HAAKE RV100/CV100流变仪等仪器,测定血液粘度、血浆粘度、红细胞比容、红细胞聚集指数、血小板聚集、复钙凝血时间(t_r)以及低切变率下凝血过程中血液粘度上升率(dη/dt)等九项流变学指标。结果表明,上述药物对凝血过程(t_r 及 dη/dt)有一定的规律性影响(P<0.05),其中破血药的抗凝血能力最强。在血液粘度及红细胞聚集指数等指标上,亦表现出随活血化瘀药物之药性增强而下降的趋势。 |
| 英文摘要: |
| Traditional herbs of promoting blood circulation and removing stasis were divideo into three groups according to their properties:circulation regulator,circulation promoter and stasis remover.Ten typical herbs were selected to feed Wistar rats with a dosage of 15g/kg for 4 days;the same volume of water was given to the control group.HAAKE Rotovisco RV100 and other related instruments were employed to determine nine hemorheologic parameters,including blood viscosity,plasma viscosity,hematocrit,index of RBC aggregation,platelet aggregation,recalcification time（tr）,blood viscosity changing rate （dη/dt）during low shear coagulation,etc.The results showed that herb property had its significant influence（P<0.05）on the process of coagulation characterized by tr and dη/dt.The anticoagulation property of stasis remover was most impressive.There was also a tendency of decreasing in blood viscosity (shear rate 21-210s-1)and the index of RBC aggregation when property of medicinal herbs was strengthened from regulating blood circulation to removing stasis. |
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