中药胃宝方加减治疗慢性胃炎100例疗效观察

作者	单位
高寿征	北京积水潭医院
吴文静	北京积水潭医院
王继侠	北京积水潭医院
甘毓麟	北京积水潭医院
邓永馨	北京积水潭医院
金树桢	北京积水潭医院
王洪琴	北京积水潭医院
危北海	北京中医研究所

摘要点击次数: 1991

全文下载次数: 1071

中文摘要:

对胃镜检查确诊为慢性浅表性胃炎或浅表萎缩性胃炎100例,经中医辨证分为脾胃虚寒、肝郁气滞、脾胃阴虚三型。分别用中药胃宝1、2、3号进行治疗(治疗组),胃宝4号用于对照观察(对照组)。3～6个月治疗组症状疗效为87.5%～91.6%,对照组62.1%,P<0.01,有显著差异。全部病例进行胃镜病理复查,治疗组病理疗效为66.2%,对照组44.8%,疗效明显优于对照组。提示中药治疗慢性胃炎疗效是肯定的。

英文摘要:

The efficiency of the herbal medicine in the treatment of 100 cases of chronic gastritis is reported.The diagnosis of gastritis was based of the principle approved by National Gastritis Meetings(1978 in Nanjing and 1982 in Sichuan).All the cases was confirmed by the gastroscopic exam and biopsy before and after treatment.According to the TCM theory it was differentiated into three clinical types:Pi Wei Xu Han(脾胃虚寒,hypofunction of the spleen and stomach with cold manifestations),Gan Yu Qi Zhi(肝郁气滞.stagnancy in the liver leading to stoppage of the flow of Qi),Pi Wei Yin Xu(脾胃阴虚,deficiency of vital essence in spleen and stomach),and used Wei Bao(胃宝) Extract No.1,No.2 and No.3 respectively.The basic components of Wei Bao Extract are:Margarita, Rhizoma Alismatis,Indigo Naturalis,Fructus Mume,Rhizoma Bletillae,Radix Glycyrrhizae,Radix Notoginseng, Rhizoma Rhei,Succinum,Olibanum.Wei Bao No.1 is added with Codonopsis pilosulae.Wei Bao No.2 is added with Radix Curcumae,Salvia miltiorrhizae,Wei Bao No.3 Herba Dendrobii,Radix Scrophulariae and Radix Paeoniae Alba.Wei Bao No.4 contains a little of Charred Triplet as control:Drugs are taken 15 gm three times per day and 3～6 months for one course.The treated groups consist of 71 cases and the control 29 cases.The rate of clinical efficiency of three groups are 87.5%,88.8%,91.6% respectively.This is significant statistically in comparison with the control group 62.1%(P<0.01).The rates of pathological improvement are 62.5%,70.4%,66.6% respectively.There is no statistic significance between the three groups and control 48.3%(P>0.05).According to our results the clinical efficiency is not paralled with the pathological improvement.The study suggests that further study should be done in order to find drugs which will contribute to pathological improvement of gastritis.

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