陈梅芳,张庆怡,吴志英,任秋华,王翔羽,张蕙芯,郑忠华,陈艳妆.玉屏风散治疗实验性肾炎的研究[J].中国中西医结合杂志,1986,(4):229-230,197 |
玉屏风散治疗实验性肾炎的研究 |
Observation on Experimental Glomerulonephritis Treated with Yu Ping Feng San(玉屏风散) |
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DOI: |
中文关键词: 玉屏风散 实验性肾炎 治疗后 实验兔 对照组 蛋白尿 病理变化 治疗机理 造型 肾小球 |
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中文摘要: |
本文观察玉屏风散对雄兔实验性肾炎的影响,证实玉屏风散对肾炎的病理修复有显著作用(P<0.001);治疗组病理好转率达83.33%,明显优于对照组。治疗组血Cr 恢复较快。作者认为其治疗机理可能与调节机体免疫能力有关。 |
英文摘要: |
A model of experimental glomerulonephritis was produced by modified Vassali method in 50 male rabbits,25 of which were treated with Yu Ping Feng San(玉屏风散,Jade-Screen Powder)and 25 as control. The left kidney was removed on the 5th week and right kidney on the 9th for light and electronic microscopic examinations.Blood creatinine,lymphocyte transformation test,and urinary protein were determined.There were much less pathological changes in the treated group than in the control(P <0.001).The rate of improvement was 83.33%in the former and 33.33%in the latter.In the 5th week blood creatinine was much lower in the treated group(P<0.05),suggesting an early improvement of renal function.There was more urinary high molecular weight protein loss in the control than in the treated.This suggests Jade-Screen Powder may have some immunoregulatory function which is beneficial to the experimental glomerulonephritis both in pathological change and in renal function. |
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