变态反应性鼻炎鼻腔细胞学改变及SIgA水平与肺肾气虚的关系

本文报道对92例变态反应性鼻炎患者鼻腔局部某些病理改变的初步观察结果。发现正常人鼻粘膜脱落细胞以鳞状上皮细胞占优势,而患者以纤毛柱状上皮细胞占优势,肺肾两虚型者较肺气虚型者更为明显。患者纤毛细胞脱落愈多,"易感冒"的发生率也愈高。患者鼻分泌物中肥大细胞数显著增多,肺气虚者较肺肾两虚者为明显。患者与对照组间 SIgA 水平无明显区别,但肺气虚组较对照组为高,肺肾两虚组较肺气虚组显著低下,文中并对上述改变作了讨论。

英文摘要:

Local pathological changes of nasal cavity were observed in 92 patients with allergic rhinitis.Shed squamous epithelial cells of nasal mucosa are dominant in normal subjects,while shed ciliated cells of nasal mucosa are dominant in patients with rhinitis,which is more obvious in the patients with energy deficiency of both the lung and kindey than in patients with energy deficiency of the lung only.Moreover,the more the shed ciliated cells are,the higher the incidence of common cold is.The mast cells in nasal secretions are found to be more in patients with energy deficiency of the lung than in patients with energy deficiency of both the lung and kidney.The SIgA level in nasal secretions is almost the same in the patients and the controls,but,that of the patients with energy deficiency of the lung is a little higher than in the controls, and markedly lower in patients with energy deficiency of both the lung and kidney. It is assumed the ciliated epithelial cells of the nasal mucosa and their functioning are damaged to varied degrees in patients with allergic rhinitis,which is even more serious in patients with energy deficiency of both the lung and kidney.So it is suggested that the count of shed ciliated cells of nasal mucosa might serve as a reference for diagnosing energy deficiency of the lung or kidney in patients with allergic rhinitis. The test of SIgA is a usable index to differentiate the different degrees of energy deficiency of this kind of patients.The increased number of mast cells in nasal secretions might suggest participation of mast cells in type I allergic reaction.The reason why the mast cells in nasal secretions are more in patients with energy deficiency of the lung than in patients with energy deficiency of both the lung and kidney awaits further research.

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