| 郑萍.血栓闭塞性脉管炎患者血瘀证的血液学指标探讨[J].中国中西医结合杂志,1986,(6):332-335,323 |
| 血栓闭塞性脉管炎患者血瘀证的血液学指标探讨 |
| The Observation of Parameters on Hematology in Thromboangiitis Obliterans of Blood Stasis Syndrome |
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| DOI： |
| 中文关键词: 血栓闭塞性脉管炎 血瘀证 免疫反应 纤维蛋白原 第八因子相关抗原 血液学指标 血小板功能 血液流变学 患者 血管壁 |
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| 中文摘要: |
| 本文探讨血栓闭塞性脉管炎患者血瘀证的血液学指标和形成血瘀证的物质基础。所测14项血液高凝指标示10项有明显异常(P<0.05～0.01);其中第八因子相关抗原的增高反映了血管内皮的损伤,提示血瘀证的产生与血管壁免疫反应所致的内皮损伤有关。 |
| 英文摘要: |
| Thromboangiitis obliterans(TAO)is considered as a blood stasis syndrome in TCM.In searching for its objective parameters of modern science and the substantial basis of blood stasis and thrombosis,14 parameters reflecting hypercoagulation and anticoagulation,platelet functions,coagulation dynamics and blood rheology were determined in 12～109 TAO patients.10 out of 14 parameters were significantly abnormal(P<0.05～0.01).Among them,the elevation of fibrinogen in the progressive stage,the elevation of PAdT and PAgT,the elevation of viscosity of whole blood and plasma and prolongation of the time of RBC electrophoresis were principally coincident to the data reported.Besides,4 parameters were significantly abnormal,i.e.,the marked elevation of HPF,Ⅷ R:Ag and·.-MG,and the reduction of AT-Ⅲ.Therefore,these 4 parameters could be considered as the supplemental parameters of blood stasis syndrome.Furthermore,the injury of vascular endothelium could be reflected from the amount of Ⅷ R:Ag,which indicated the close relationship between the formation of blood stasis syndrome and the immunoresponse injured vascular endothelium,and that was presumed most probably as the substantial basis of blood stasis syndrome and thrombosis. |
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