| 巫协宁,郑惠英,徐仁淇,周中介,李元元,王延芳.中国H3与六味地黄丸治疗更年期综合征的疗效比较[J].中国中西医结合杂志,1986,(6):336-338,323 |
| 中国H3与六味地黄丸治疗更年期综合征的疗效比较 |
| Comparative Effectiveness of Chinese H3 and Liu Wei Di Huang Wan in the Treatment of Female Climacteric Syndrome |
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| DOI： |
| 中文关键词: 六味地黄丸 妇女更年期综合征 阴道脱落细胞 有效率 绝经后 更年期症状 服药 微量雌激素 下丘脑 手术后 |
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| 中文摘要: |
| 对手术后绝经、自然绝经2年与绝经前后患更年期综合征妇女进行 CH3与六味地黄丸的对比观察示:CH3与六味地黄丸改善症状的显效与有效率相同,分别为39%与61%,服用一年疗效持续而稳定;CH3组 FSH、LH、E2水平服药前后无明显变化（P>0.05）,而六味地黄丸组 FSH 降低（P<0.05）,E2升高（P<0.05）,LH 无变化;阴道脱落细胞成熟值二组均无明显变化。CH3是通过 cAMP 增强体内微量雌激素产生效用,而六味地黄丸则可能通过下丘脑—垂体—性腺轴起作用。 |
| 英文摘要: |
| Observations on the comparative effectiveness of Chinese H.(CH.)and Liu Wei Di Huang Wan (LWDHW)on patients with menopause after surgery,menopause by nature for 2 years,and female climacteric syndrome before and after menopause,show identical rates of marked improvement and effectiveness,which are 39% and 61% respectively.Long-term intake for one year gives steady results. Change of FSH,LH,E.levels before and after CH.are not statistically significant(P>0.05),whereas in the case of LWDHW group,FSH declines(P<0.05),E.increases(P<0.05),but there is no change in LH. Maturation value of exfoliative cells of vaginal epithelium in the two groups do not show significant changes.The mechanism of action of CH.is mediated through the celltdar increase of cAMP which enhances the action of traces of estrogen present in the body:LWDHW probably acts through the hpothalamic-pitultary-gonadal axis. |
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