苎麻根液治疗上消化道出血疗效观察

作者	单位
李良胜	江西吉安地区人民医院内二科
王冠庭	上海第二医学院附属瑞金医院内科
胡永立	江西吉安地区人民医院内二科
刘毅然	江西吉安地区人民医院内二科
吴正宙	江西吉安地区人民医院内二科
罗贤陶	江西吉安地区人民医院内二科
刘振国	江西吉安地区人民医院内二科
孙丹莉	江西吉安地区人民医院内二科

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中文摘要:

本文85例上消化道出血患者分两组进行治疗观察,观察组(55例)用苎麻根液治疗,疗效优于对照组(P<0.05),以喷射加口服法最佳,单纯口服法次之,单纯喷射法最差,同时就用药方法与疗效关系及本药作用机制等问题加以讨论。

英文摘要:

This paper reports 85 cases of acute upper digestive tract bleeding that were admitted from Dec.1981 to May 1984 with traditional Chinese medicine or Western medicine exclusively.Among these,63 were male and 22 were female,aged.14 to 76 years(mean 37.5).The diagnoses were confirmed by means of examination of gastroscopy,These cases were divided into two groups randomly.55 cases belonged to the observation group,of which 23 patients were treated by oral therapy(alcoholic extract of Radix Boehmoriae,RB),200 to 300% 10～30 ml three times everyday was given till one day after the negative conversion of stool occult blood test,while 30～60 ml of the above herbal fluid was sprayed directly to the bleeding lesion through direct vision of gastroscopy for 10 cases.The other 22 cases were given the combined oral and spray therapy.60 cases of the control group were given intravenously the dicynonum 750 mg added to 5% glucose saline 200～500 ml once daily,and adrenosin 10 mg was given intramuscularly twice a day,till one day after the stool occult blood test became negative. The effective rate of RB group was 94.54%,the average time for the negative conversion of stool occult blood test was 2.48 days.While those of the control group were 76.66% and 4.3 days respectively,which was significantly different(P<0.05).The hemostatic effect of RB is satisfactory,the combined therapy is the best which may raise the efficacy.The oral and spray method may be complementary to each other;oral administration the second and the spray method the third.RB has adhesive and astringent effect,which may be its chief mechanism of hemostasis.

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