甘芍降糖片治疗214例糖尿病患者的疗效初步观察

作者	单位
王宗根	上海医科大学附属华山医院内科学教研组内分泌组
胡国贤	上海医科大学附属华山医院内科学教研组内分泌组
朱禧星	上海医科大学附属华山医院内科学教研组内分泌组
龚伯强	上海中药制药一厂
钟学礼	上海医科大学附属华山医院内科学教研组内分泌组

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中文摘要:

本文报道用甘芍降糖片治疗214例糖尿病患者,单用者180例,中西医综合治疗者34例。其总有效率为74.8%。200例中(单用本药180例,综合应用20例)用药前血糖均值为213.16mg/dl,用药后降至166.66mg/dl,平均下降46.50mg/dl(P<0.001)。最后对其临床疗效、作用机理、副作用及注意事项等作了讨论。

英文摘要:

This paper presents the therapeutic effect of Ganshao Jiangtang Tablet(甘芍降糖片)consisting of Radix Paeoniae albae and Radix Glycyrrhizae uralensis,which is used in 214 diabetes mellitus patients. Among them,180 cases were treated with this composite tablet alone,and other 34 cases treated with this tablet and western medicine together.Patients’ urine sugar was tested with 61 markedly effective cases (28.60%),85 effective cases(39.70%)and 14 improved cases(6.50%).Changes of blood sugar concentration before and after the treatment were observed in 152 cases.Before treatment,only 36 cases ranged 100～199 mg/dl of blood sugar,while after treatment,the cases increased to 96.For equal and over 200 mg/dl,the patients were 39 and 56 respectively(P<0.01). According to blood sugar changes of 200 gases,180 cases treated with this tablet alone and 20 cases combined with other drugs,the mean value before and after treatment was 213.16 mg/dl and 166.66 mg/dl respectively.The average decrease was 46.50%(P<0.01). Finally the effectiveness,mechanism of hypoglycemic action and side-effect of this tablet wore discussed. The indication and administration of the drug are as follows:(1)In cases of mild or moderate type Ⅱ(adult type)of diabetes mellitus patients,this tablet can be used alone o.combined with other hypoglycemic drugs including insulin;while in severe cases,it must be used with insulin simultaneously.It is not indicated for the patients of type Ⅰ diabetes mellitus.(2)It must not be given alone to the patients suffering from acute complications,for instance,acute infection,acetonemia and acidosis,or in the state of severe stress responses.(3)The Ordinary dose is 3～4 tablets,3 times a day after meal and the dosage can be increased in patients with poor responses,but the maximal dose is 8 tablets each time and no more than four times a day.

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