| 张亭栋,李元善,李成文,马玲.AOAP方案治疗急性非淋巴细胞白血病临床观察[J].中国中西医结合杂志,1986,(10):602-603,581 |
| AOAP方案治疗急性非淋巴细胞白血病临床观察 |
| Clinical Observation on the Effect of AOAP Programme in Acute Non-Lymphatic Leukemia |
| 免费下载全文 查看/发表评论 下载PDF阅读器 |
| |
| DOI： |
| 中文关键词: 急性非淋巴细胞白血病 完全缓解率 临床观察 方案 辨证施治 总缓解率 部分缓解 白血病细胞 诱导治疗 细胞动力学 |
| 英文关键词: |
| 基金项目: |
|
| 摘要点击次数: 1530 |
| 全文下载次数: 971 |
| 中文摘要: |
| 本组27例急性非淋巴细胞白血病以 AOAP 方案结合辨证施治进行临床观察,结果:完全缓解10例,完全缓解率37.03%;部分缓解9例,部分缓解率33.33%;总缓解率为70.37%。本方案治疗诱导时间短,副作用小,疗效较为满意。 |
| 英文摘要: |
| Twenty seven cases of definitely diagnosed acute nonlymphatic leukemia（four M1,ten M2,eight M3,one M5 and four M6 types）were treated with AOAP programme（Ailin-l injection,Oncovin,Ara-C, Prednisone）.A seven-day course of treatment was repeated with a ten to fourteen-day interval between every two treating courses until complete remission.During all the periods of treatment and interval,a dose of Chinese herbal decoction was taken daily according to the syndrome differentiation of the patient. Total rate of remission was 70.37%.Among them,complete remission in 10 cases（37.03%）consisting of two M1,two M2,four M3,one M5 and one M6 type was obtained,with a remission period ranged 25 to 172 days（median period:56 days）.2 to 4 courses of treatment were necessary for causing remission.Two of them relapsed,but another period of complete remission was obtained by the same therapy.Partial remission was obtained in 9 cases（33.33%）consisting of five M2,two M3 and two M6 types.8 patients were ineffective to this programme. AOAP programme,in which the principal drug is Ailin-l injection,and other chemicals were designed in light of cell cycle kinetics and the mechanism of dual synchronization.The clinical application showed better efficacy.This programme induced no toxic reactions of heart,liver,kidney and other organs except for some adverse gastrointestinal responses. |
| 关闭 |
|
|
|
扫描微信二维码，获取更多信息