甜菊治疗高血压病的临床观察

作者	单位
周有录	新疆石河子医学院附属医院内二科
李玉珊	新疆石河子八一糖厂职工医院
来雪莲	新疆石河子八一糖厂职工医院
罗国良	新疆石河子医学院附属医院内二科

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中文摘要:

本文应用国产甜菊甙治疗高血压病31例,并以23例高血压病患者服安慰剂作对照。每次甜菊甙0.5g,一日三次口服,30天为一疗程。结果显效18例(58.1%),有效8例(25.8%),无效5例(16.1%),总有效率83.9%;对照组有效率为8.6%。两组差异非常显著(P<0.01)。服药后未发现血脂升高,副作用亦少而轻。其降压机制尚待研究,可能与利尿有关。

英文摘要:

Among all the 54 patients suffering from hypertension,31-were treated with Chrysanthemum morifolium glucoside and the remaining 23 as the control group,a placebo.The dosage was 0.5 g in capsule, three times a day.The course of treatment was 30 days.Hypertension was diagnosed according to the standard of WHO.Measurement of blood pressure and evaluation of therapeutic efficacy were determined by complying with unified national standards and levels.Results:18 cases(58.1%)were marked effective,8 cases(25.8%)effective.5 cases(16.1%)non-effective.The total effectiveness was 83.9% and the control group 8.6%.The difference between these two groups was significant(P<0.01).The effectiveness of the first stage hypertensives was more distinct than that of second and third stage.Before and after receiving treatment,the ECG of the patients showed no evident improvement or deterioration.As to blood lipids,the mean value of cholesterol and β-lipoprotein showed a slight reduction and no increase at all.Side-effects such as slight flatulence,acid regurgitation,nausea and headache appeared among a few patients.It was, however,unnecessary to stop medication or taking any other measures.They would disappear by themselves.The amount of urine was increased and the blood pressure decreased evidently one week after taking drugs.Possibly its hypotensive effect was relevant to the diuresis.

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