中西医结合治疗肺心病患者的阻抗肺血流图变化

作者	单位
李廷谦	华西医科大学附属医院
陈文彬	华西医科大学附属医院
黄素珍	华西医科大学附属医院
戢朝明	华西医科大学附属医院
张玉兰	华西医科大学附属医院
李桂英	华西医科大学附属医院

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中文摘要:

本文以清热解毒和活血化瘀为治则的复方中药内服、丹参注射液静脉滴注及常规应用的西药治疗肺心病急性发作期患者80例。治疗20天后检测阻抗肺血流图的8项参数,其中 B-y 间期、b-s 间期、波幅及肺动脉压与治疗前比较,均有显著性差异(P<0.05～0.01)。结果说明,中西医结合治疗对肺心病患者改善缺氧、纠正酸中毒、降低肺动脉压及改善心功能等方面均有重要的作用。

英文摘要:

Eighty cor pulmonale patients in acute exacerbation stage were treated with TCM-WM therapy,which comprised TCM compound prescriptions based on the principle of Qingre Jiedu(清热解毒,clearing up the heat and removing the toxic substance)and Huoxue Huayu(活血化瘀,promoting the blood circulation and relieving the stasis)orally taken,Salvia injection intravenously dripping as well as drugs of WM routinely used.An investigation on the changes of impedance puhnonary rheogram(IPR)in patients with cor pulmonale in acute stage were noticeably abnormal compared with normal control group(P<0.01).After 20 days of treatment in patients with cor pulmonale by TCM-WM therapy,the B-y interval,b-s interval of IPR indices and amplitude of IPR were significantly increased(P<0.05～0.01),and the pulmonary hypertension also markedly improved(P<0.01)as compared with the condition before treatment.However,no definite change in the remaining 4 IPR indices between the pre-and post-treatment was found.The results indicated that the TCM-WM treatment played an important role in the alleviation of hypoxia,correction of acidosis, reduction of pulmonary hypertension and improvement of cardiac function in acute stage of cot pulmonale.

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