| 林兰,张鸿恩,高齐健,王毓钟,闪增郁.降糖甲片治疗糖尿病38例的左心功能测定初步观察[J].中国中西医结合杂志,1987,(3):148-150,132 |
| 降糖甲片治疗糖尿病38例的左心功能测定初步观察 |
| Clinical Observation of Adult Diabetes Mellitus Treated with Jiang Tang Jia Tablet—Left Ventricular Functional Determination in 38 Cases |
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| DOI： |
| 中文关键词: 降糖甲片 左心功能 心功能测定 糖尿病患者 治疗后 纤维蛋白原 初步观察 治疗前后 血浆胰岛素 统计学处理 |
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| 中文摘要: |
| 对用降糖甲片治疗的38例糖尿病患者,作左心功能测定观察,结果提示:随着血糖、尿糖、血胆固醇、纤维蛋白原下降,血浆胰岛素升高,糖耐量改善,心功能也有所改善,LVET 延长,PEP 缩短.PEP/LVET 比值下降,经统计学处理,上述各项指标治疗前后比较均有显著性差异(P<0.05或<0.01)。 |
| 英文摘要: |
| The clinical application of non-invasive left ventricular determination has proved that the systolic time interval(STI)was a good parameter in evaluating the ventricular function and the pharmaceutical effect of the drugs.Jiang Tang Jia tablet consisted of Astragalus membranaceus,Polygonatum sibiricum, Pseudostellaria heterophylla,Rehmania glutinosa and Trichosanthis kirilowi had been used in treating 38 cases of diabetes mellitus with deficiency of Qi(气)and Yin(阴)syndrome.Their left ventricular function was checked.Results:As the lowering of blood and urine sugar,the heart functions improved,the left ventrieular ejection time(LVET)has been extended from 286.62±9.48 ms to 298.18±10.65 ms.It showed that before treatment,the heart ejection time was shortened,heart output reduced,it recovered to a certain degree after the therapy.The pre-ejection period(PEP)decreased from 118.41±11.54 ms to 107.20±14.00 ms,which denoted that before treatment,the cardiac function was markedly deteriorated,but enhanced somewhat after medication,the ratio of PEP/LEVT was less than 0.38,it is generally accepted as the most reliable criteria in evaluating the left ventricular function.In this group,the PEP/LVET lowered from 0.42±0.07 to 0.40±0.07,it indicated that the myocardium impairment and cardiac function disturbance were significantly improved.It elevated the level of plasma insulin,improved the glucose tolerance,lowered the blood lipid,fibrinogen and its catabolic substance.This beneficial effect may be due to regulating the Yin-Yang(阴阳)of the body,replenishing the Qi and Yin,and thus enhancing the function of heart and islets of pancreas. |
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