通管汤对家兔输卵管炎的抗炎作用

本文采用苯酚糊剂造成家兔化学损伤性输卵管炎症模型,以用药组及非用药组家兔的组织学切片及用药前后的血液流变学测定作为观察指标进行通管汤的抗炎作用研究。结果表明,通管汤具有对抗输卵管炎变的效应,并提示此种效应可能是通过改善组织细胞代谢,抑制成纤维细胞增生,减少炎细胞浸润,以及降低血液粘滞度和血中大分子物质的聚集性,从而改善血液流变性,纠正局部血循环障碍而实现的。

英文摘要:

Phenol-induced chemical salpingitis of rabbit was thosen as experimental model.Two groups were formed.Tong Guan decoction(通管汤)group and control group.After medication,pathological examination was done on both groups.The result of the experiment has proved that Tong Guan decoction was effective on chemical salpingitis.The difference between these two groups was significant statistically,(with Ridit method,95% believable limit was no interlock).The effect was brought about by improving the cell metabolism,inhibiting the hypcrplasia of fibrocytes and reducing the infiltration of inflammatory cells.The difference was also significant between these groups both in salpingian epithelium,submucous and serous membrane.The indices concerning rabbit’s hemorheology were also analysed before and after medication.It indicated that Tong Guan decoction could improve the viscosity of blood and aggregation of blood cell.The blood flow was increased in inflammatory area,and the circulatory disturbance was corrected.The differences of the indices between pre-and post-treatment were significant,P<0.05 and P<0.001.

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