生脉口服液对老年大鼠肝脏组织化学成分的影响

作者	单位
张国玺	中国中医研究院西苑医院
刘志云	中国中医研究院西苑医院
李彩熙	中国中医研究院西苑医院
金龙	中国中医研究院西苑医院
周文泉	中国中医研究院西苑医院
李连达	中国中医研究院西苑医院
陈可冀	中国中医研究院西苑医院

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中文摘要:

本文通过动物实验,观察了生脉口服液对老年大鼠体重、体力及肝脏组织化学成分的影响。结果表明:生脉口服液对老年大鼠的体重无影响,但能够明显地增强动物的体力。同时能提高老年大鼠肝脏内琥珀酸脱氢酶的活性,增加肝脏内核糖核酸和糖原的含量。提示生脉口服液有增强老年大鼠体力和肝细胞机能的作用。

英文摘要:

zz healthy aged rats(18 month old)were selected for this experiment.The animals were divided randomly into treated and control groups.These two groups were treated with Sheng Mai Liquor(10 ml/kg per day)and normal saline(10 ml/kg per day)respectively for 3 weeks.The body weight and physical strength were measured before they were sacrificed.The liver was excised and put into the cryostat section and the histochemical reactions with succinate dehydrogenase(SDH),lactate dehydrogenase(LDH), monoamine oxidase(MAO),RNA and glycogen were carried out.The experimental results showed that there was no change on body weight of the aged animals in the treated group,but physical strength were enhanced. The activity of SDH was elevated significantly and the content of RNA and glycogen were increased markedly in the liver of aged rats of treated group than that of the control.But there was no significant difference of hepatic LDH and MAO between these two groups.The results suggest that Sheng Mai Liquor itself may enhance the aged rats’ physical strength and promote the functional activity of liver in the aged rats.

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