精神分裂症甲皱微循环观察与中西医结合治疗

本文实验结果发现,120例精神分裂症患者甲皱微循环的管袢数目、管长、管径、流速、流态、形态与100例健康人比较(P<0.01),异常率达70%。用活血化瘀药配小剂量抗精神病药治疗60例,显效率达75%,与单用活血化瘀药治疗的60例显效率45%作对照比较,P<0.005。对40例患者作了治疗前后甲皱微循环观察比较,差异非常显著,并发现症状的改善和微循环异常的改善大致相平行。

英文摘要:

The analysis of the naiifold microcirculation was made between 120 schizophrenia patients and 100 healthy subjects as control.The shape,width,length,order and clearness of the nailfold capillary loops as well as the speed and status of blood flow of the nailfold microcirculation in 70% of patients were abnormal,being significantly higher than 30% of control.50% of the patients showed features of blood stasis in the tips of the capillary loops.The patients were randomly divided into two groups. 60 patients in group Ⅰ were treated with drugs of"promoting the blood circulation and relieving the stasis"(PBCRS),such as Salvia miltiorrhiza,Sparganii stoloniferum,Citrus aurantii immaturalis, Rheum palmatum.The effective rate in group Ⅰ was 45%.60 patients in group Ⅱ were treated with both the drugs of PBCRS and anti-schizophrenia Western medicine.The effective rate in group Ⅱ was 75%,significantly higher than that of group Ⅰ,showing that there existed synergism between these two kinds of drugs.In addition,the changes of the clinical manifestation with that of the nailfold microcirculation before and after treatment in 40 schizophrenia patients were compared,and found that the improvement of the clinical manifestation was parallel to that of the nailfold microcirculation.

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