凉血活血法不同组方对27例重度黄疸肝炎消退黄疸及改善病理的比较

Comparison of the Pathology-Improving and Jaundice-Reducing Effects of Different Prescriptions of Blood-Cooling and Circulation-Promoting Prescriptions for 27 Cases of Severe Icteric Hepatitis

免费下载全文查看/发表评论下载PDF阅读器

DOI：

中文关键词: 血清胆红素辨证论治凉血活血法肝活检统计学处理随证加减协定处方合剂肝脏病理胆汁郁积

英文关键词:

基金项目:

作者	单位
贺江平	中国人民解放军三○二医院
汪承柏	中国人民解放军三○二医院
朱纯吾	中国人民解放军三○二医院
李森	中国人民解放军三○二医院
徐丽芳	中国人民解放军三○二医院

摘要点击次数: 1333

全文下载次数: 1022

中文摘要:

本文以葛根、赤芍、丹参等3～5味中药为主药随证加减组成辨证组(14例),以此为基础制成合剂组(13例)。两组病例均经临床、生化确诊,24例有肝活检证实。两组用药时血清胆红素为10.0～54.1(平均22.35±11.09)及10.3～46.8(平均26.36±10.12)mg/dl;分别有8及7例做了治疗前后肝活检比较。治后黄疸均消退。两组的黄疸消退有效率、速度及改善病理同以往用大处方治疗者比较,经统计学处理均无显著性差异,提示在坚持辨证论治前提下,精简处方乃至制成合剂,可保持原有疗效,并有利于推广使用。

英文摘要:

By reducing some medicinal herbs in the former blood-cooling and circulation-promoting prescriptions’with heavy dosages of Paeonia rubra,new prescriptions with only 3～5 principal herbs such as Pueraria tobata,Salvia miltiorrhiza and Paeonia rubra were formed with their dosages changed according to each patient’s symptoms,which was the syndrome differentiation(SD)group. Based on this,some mixtures were prepared and used,which composed the mixture group.14 and 13 cases with their diagnosis established in clinical practice and confirmed by liver biopsy were treated with the new simplified prescriptions and mixtures respectively.Their serobilirubin was 10. 0～54.1(22.35±11.09 in average)and 10.3～46.8(26.36±10.12 in average)at the time when the treatment began.Liver biopsies were conducted for 8 cases in the SD group and 7 in the mixture group before and after treatment.All of the patients’serobilirubin normalized after treatment.The average time for the lowering of bilirubin to less than 10 g/dl and 5 mg/dl was 27.33±14.83 days and 41.29±26.23 days for the SD group,and 21.0±9.32 days and 29.33±15.38 days for the mixture group. No significant difference was found in jaundice-reducing and pathology-improving effect between the cases receiving new prescriptions and mixtures and those receiving blood-cooling and circulation- promoting Chinese medicinal herbs with heavy dosage of Paeonia rubra.The present study suggested that following the principle as"treat the patient according to syndrome differentiation",the sim- plified new prescriptions and mixtures might keep the same efficacy as the former big prescription, and its application should be promoted.

关闭