| 杨梅香.龟上、下甲药理作用的比较研究[J].中国中西医结合杂志,1988,(5):279-281,262 |
| 龟上、下甲药理作用的比较研究 |
| Comparative Study on Pharmacological Function of Back-Shell and Plastron of Tortoise |
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| DOI： |
| 中文关键词: 药理作用 比较研究 大鼠 免疫功能 阴虚 微量元素 甲亢 含量测定 皮下注射 甲状腺功能 |
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| 中文摘要: |
| 本文采用 T3皮下注射造成大鼠甲亢阴虚模型,从甲状腺、肾上腺、免疫功能及微量元素等二十余项客观指标,比较龟上、下甲的滋阴药理作用。结果证实,龟上、下甲具有相同的滋阴作用,并测得二者毒性均极低。为龟上、下甲同等入药提供了实验依据。 |
| 英文摘要: |
| In this dissertation,the results of a comparative study on the pharmacological function and toxicity of back-shell and plastron of tertoise are reported.Since most of the patients with hyperth- yroidism were characterized by Yin（阴）-deficiency,rats were prepared as animal models with Yin-deficiency,induced by subcutaneous injection of T3 50 μg/100g.Over 20 indices on the function of thyroid gland,adrenal gland,immunoactivity and trace elements,which were considered vital in diagnosing Yin-deficiency,were measured.The results,indicate that both back-shell and plastron of tortoise possess identical Yin-nourishing property.The mechanism of Yin-nourishing is closely related to decreasing the function of thyroid and adrenal gland,increasing the function of im- munoactivity as well as the decreasing of Cu in serum.The maximal tolerant doses（MTD）-250 g/kg prepared from back-shell and plastron are respectively tried on mice,demonstrating very low toxicity.It is thus evident that the above results provide laboratory evidence for the equal utilization of back-shell and plastron. |
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