| 谢道珍,周绍华,孙怡,赫希格,常珍,张宝利,贾敏,魏玉群,何巍,陈雨恒,王岚芬,李涛.脑血康治疗高血压性脑出血的临床与实验研究[J].中国中西医结合杂志,1988,(6):341-343,324 |
| 脑血康治疗高血压性脑出血的临床与实验研究 |
| Clinical Observations and Experimental Studies on Naoxuekang in Treating Hypertensive Cerebral Hemorrhage |
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| DOI： |
| 中文关键词: 高血压性脑出血 脑血康口服液 手术治疗 总有效率 显著性 作用机理 中西药治疗 血肿吸收 外侧型 中药治疗 |
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| 中文摘要: |
| 本文报道高血压性脑出血患者306例,A 组(中药组)180例,用脑血康治疗,痊愈加显效占80.5%,总有效率为90%。B 组(对照组)126例,其中西药治疗616例,痊愈加显效占66.7%,总有效率为81.8%,手术治疗60例,痊愈加显效占61.7%,总有效率为83.3%。A 组与 B 组疗效比较,P<0.01,差异有非常显著性意义。表明,A 组疗效优于 B 组。通过动物实验初步探讨了本药的治疗作用机理。 |
| 英文摘要: |
| This paper reports the clinical observations and experimental studies in treating hypertensive cerebral hemorrhage with Naoxuekang.306 cases of hypertensive cerebral hemorrhage with similar conditions have been observed,of which 180 cases formed group A which has been treated with Naoxuekang for 4～6 weeks while the remaining 126 cases formed group B as control,which has been subdivided into two subgroups:66 cases were treated by Western medicine(WM)and the other 60 rases were treatco with surgical operation.Results indicated the total effective rate of group A was 90%.The rate of cure and marked improvement was 80.5%.In WM group and surgical operation group,the rates were 81.8% and 83.3%,66.7% and 61.7% respectively.The difference was significant statistically(X~2=19.11,P<0.01).Naoxuekang is an oral liquid.The remedy is composed of ingredi- ents extracted from Chinese materia medica,which contain various kinds of amino acids, anticoagulin and other chemical substance.The clinical observations and experimental studies showed that the Naoxuekang could improve cerebral anoxia and microcirculatory disorder,reduce blood pressure,promote dissolution of fibrin and stimulate the phagocytosis of macrophages,so as to promote absorption of cerebral hematoma and benefit the recovery of neural function. After discussion,a conclusion could be drawn that when the quantity of hemorrhage is less than 40 ml or the hematoma is an external localized one and the patient is in mild disturbance of consciousness,good curative effect could be expected. |
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