艾炷灸对大肠杆菌内毒素致热家兔体温及微循环的影响

本实验以家兔耳静脉注射大肠杆菌内毒素复制发热模型,将致热家兔分为施灸组和对照组,施灸组致热后立即在大椎穴施以艾炷灸,对照组置艾炷不点燃,观察两组家兔5小时内发热效应。结果表明,艾炷灸对大肠杆菌内毒素感染性发热家兔有明显退热作用。比较两组家兔球结膜微循环,提示艾炷灸能明显改善大肠杆菌内毒素感染性发热家兔的微循环。此外,实验中观察到艾炷灸对正常家兔体温无明显影响。

英文摘要:

In order to explore the role of moxibustion as antipyretics,this paper studied the effect of moxibustion on temperature and microcirculation in rabbit fever model caused by colitoxin which simulated fever model caused by exogenous pathogenic factors.The febrile rabbits were divided into two groups:one was moxibustion group(MG)which was moxibusted at Dazhui(GV14)point immedi- ately after the fever was induced,the other was control group(CG)which was not moxibusted,but moxa-cone was placed on the Dazhui.The pyretic effect of these two groups was comparatively observed between MG and CG.Results showed that the fever incubation period in MG was shortened, the fever tracing become left-shifting,the sustained time of fever reduced,the maximal peak of fever lowered,the temperature response index decreased.In comparing the values with that of CG,the differences of all the above-mentioned parameters were significant(P<0.01).It suggested moxibus- tion had antipyretic effect on the fever of rabbits caused by colitoxin obviously.But the effect of moxibustion on temperature of normal rabbits was not remarkable.The microcirculation of conjunctiva of febrile,rabbits was observed with microcirculatory microscope.The results showed that the speed of blood flow was fast,the numbers of open capillary network increased,the color of blood brightened,the perimicrovascular effusion decreased.It indicated that moxibustion was able to improve microcirculation of colitoxin induced febrile rabbits and eliminate the inflammation,the temperature was lowered.After moxibustion,the rabbits’auricle became obviously congested, temperature of crus helicis was higher than the control,the cross points increased markedly,the blood flow accelerated as well.All of these showed the relationship between the antipyretic effect of moxibustion and heat-dissipation.The experiment provided evidence for"heat syndrome could be treated with moxibustion".

关闭