| 胡业彬,钱振淮,翁维良,王怡,刘剑刚,葛争艳,李醒华,戴梅芳,涂秀华.活血冲剂治疗冠心病心绞痛血瘀证的临床及血液流变性研究[J].中国中西医结合杂志,1988,(10):599-600,581 |
| 活血冲剂治疗冠心病心绞痛血瘀证的临床及血液流变性研究 |
| Clinical and Hemorrheologic Study in Treating Blood-Stasis Syndrome of Angina Pectoris with Huoxue(活血)Granule |
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| DOI： |
| 中文关键词: 冠心病心绞痛 血液流变性 红细胞变形能力 活血 不稳定心绞痛 全血粘度 血栓弹力图 冲剂 凝固时间 冠心病血瘀证 |
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| 中文摘要: |
| 用活血冲剂治疗冠心病心绞痛血瘀证50例,结果表明:活血冲剂有缓解心绞痛、改善缺血性 ECG 改变的作用;并可抑制血小板粘附性和聚集性,降低低切速下的全血粘度,改善红细胞变形能力,延长血栓弹力图的反应时间和凝固时间。提示其缓解心绞痛与改善血液流变性有关,是治疗冠心病血瘀证较理想的药物。 |
| 英文摘要: |
| This paper reports treating blood-stasis Syndrome of coronary heart disease(CHD)angina pectoris with Huoxue granule(HXG)and its effect on hemorrheology.50 cases were divided into two groups,one group was treated with HXG,another with placebo(single blind).In HXG group the total effective rate for angina pectoris was 86.7%,marked effective rate 33.3%,effective rate for ischemic ECG changes was 40%.All of these were better than placebo group statistically(P<0.025,0.005, 0.025).Experimental results showed that HXG was able to inhibit platelet adherence and aggrega- tion,decrease whole blood viscosity in low shear, prolong reacting time and coagulating time of thrombolastrogram,improve erythroid deformability.So the mechanism for HXG in treating angina pectoris may be preventing coronary artery injury caused by platelet adherence,aggregation,release and hypercoagulation,improving microcirculation and myocardial blood supply These results suggest that HXG is an effective antianginal medicine. |
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