血府逐瘀汤对气滞血瘀型高脂血症降脂作用的临床观察与实验研究

血府逐瘀汤治疗气滞血瘀型高脂血症患者20例,在气滞血瘀证明显改善的同时,血清 TC 和 TG 也显著降低结果提示:气滞血瘀证可能与血脂的升高存在一定的关系,血府逐瘀汤对气滞血瘀证患者的血脂升高有一定的降低作用。动物实验结果:方中的理气药能降低高脂大鼠血清 TC、TG、LDL-Ch 和肝 TC,方中的活血药能降低其肝 TC、TG和肝指数。表明理气药和活血药在调节脂质代谢方面有协同作用。

英文摘要:

Xuefu Zhuyu Tang(XFZYT,血府逐瘀汤)was used in 20 cases of hyperlipidemia with Qi stagna- tion and blood stasis syndrome(QSBS).The results were that the symptoms of QSBS have markedly improved,and the levels of serum TC and TG have decreased,especially on TG(P<0.001).It showed that QSBS was probably in certain connection with increasing serum lipids,and XFZYT could decrease them.The results of experiment were as follows:the regulating Qi(RQ)herbs,a component in XFZYT,decreased the levels of serum TC,TG,LDL-ch,and liver tissue’s TC in hyperlipidemic rats;the promoting blood circulation(PBC)herbs,another component in XFZYT,decreased the levels of liver tissue’s TC,TG and liver index on hyperlipidemic rats;XFZYT had the effect of both components,it decreased either the levels of serum TC,TG and LDL-ch,or the liver tissue’s TC,TG and liver index.So we consider that RQ and PBC herbs in XFZYT probably work in coordination on regulating the metabolism of lipids.

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