| 秦万章,向熙瑞,吴文媛,杨春欣,吴惠莉,秦立(?),顾(?).三藤糖浆治疗302例各型红斑性狼疮的临床观察[J].中国中西医结合杂志,1988,(10):604-606,582 |
| 三藤糖浆治疗302例各型红斑性狼疮的临床观察 |
| Clinical Observation of Three Lianas Syrup in Treating 302 Cases with Various Types of Lupus Erythematosus |
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| DOI： |
| 中文关键词: 红斑狼疮 糖浆 临床观察 红斑性狼疮 对照观察 细胞免疫 免疫核糖核酸 治疗方法 雷公藤 疗效 |
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| 中文摘要: |
| 本文报道采用具有活血凉血和养血功能的三藤糖浆治疗302例各型红斑狼疮,其中包括 DLE58例、cLE23例 SLE180例、OLE10例及 MCTD31例。治疗结果288例取得不同程度的疗效,有效率为95.4%,对照观察提示三藤糖浆疗效均院于各对照组免疫核糖核酸(iRNA)与三藤糖浆合并用于红奇狼疮,可以进一步提高疗效。临床观察和免疫研究说明三藤糖浆的治疗作用在于调节抗体形成,增强细胞免疫,以及增强NK 细胞的活性。 |
| 英文摘要: |
| 302 cases with various types of lupus erythematosus(LE),including 58 cases of chronic discoid LE iDLE).23 cases of subacute cutaneous LE(ScLE),180 cases of systemic LE(SLE),10 cases of overlapping LE(OLE)and 31 cases of mixed connective tissue diseases(MCTD)were treated with Three Lianas Syrup(TLS).Improvement after treatment was observed in 288 cases(95.4%)within 1～3 weeks,arthralgia,fever and skin lesions were greatly improved.The visceral involvment and immunological parameters was also improved.Decrease of dosage or withdrawal of corticosteroid was also an aspect of improvment.The therapeutical effect of TLS was-better than any other control group.Above data showed that TLS inhibited the polyclonal antibody strains of B cells and improved the regulation of antibody formation,TLS may activate cellular immunity especially NK cells,which are important in immune surverlance in LE and the activation of NK cells perhaps is the essence of pharmacological action of TLS. |
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