补肾法对老年慢性支气管炎患者T细胞亚群及其免疫功能的作用

作者	单位
章育正	上海中医学院微生物教研室
杨蕊英	上海中医学院微生物教研室
赵慧娟	上海中医学院微生物教研室
陈永亮	上海中医学院微生物教研室
李文	上海中医学院曙光医院免疫室
姚培发	上海中医学院龙华医院老年病组
林水淼	上海中医学院龙华医院老年病组

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中文摘要:

本文观察到肾虚型老年慢性支气管炙患者的 OKT₃、OKT₄细胞和 OKT₄/OKT₈的比值明显低于对照组（P<0.01）,OKT₃细胞则高于对照组（P<0.05）;其他免疫指标如 E-花环百分率、补体₃均低于正常值,免疫球蛋白呈紊乱现象。经补肾法治疗后,OKT₃及 OKT₄细胞比治疗前有明显升高（P<0.01）,与对照组比差异无显著性（P>0.05）,OKT₈细胞下降,与对照组比差异无显著性（P>0.05）。其他免疫指标也相应趋于正常。

英文摘要:

In order to observe the changes of the T-cell subset in OKT system by treatment of Tonifying- Kidney herbs for three months,30 cases of chronic senile bronchitis of Kidney-asthenia were chosen and examined.the E-rosette%,C₃ and immunoglobulin content also detected and compared with it. The results showed that total numbers of T-cell（OKT₃）of the patients were lower than those of normal individuals（P<0.01）and it coincided with the result of E-rosette%.The TH/TI numbers （OKT₄）were also markedly decreased（P<0.01）.The TS/TK cell numbers（OKT₈）were elavated（P< 0.05）and the OKT₄/OKT₈ ratio was obviously decreased as compared to the normal individuals（P< 0.01）.After treatment with Tonifying-Kidney herbs,the general symptoms of patients were im- proved,and patient’s OKT₃ and OKT₄ were higher than that of pretreatment（P<0.01）.The OKT₈ was followed to normal level OKT₄/OKT₈ ratio was a litle but not evidently increased after treatment.E-rosette% also elevated as normal individuals. IgG and IgM contents in serum of the patients were higher than that of the normal group（P< 0.01 and 0.05）.After treatment,IgM content was decreased to normal level,but IgG content was not markedly decreased.IgA content was still in normal level.C₃ content of the patients had never changed markedly after treatment. The above mentioned results showed that immune function of patients of Kidney-asthenia was discrThe tonifying-Kidney herbs can regulate the distribution of the T-cell subset in senile

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