冠心病气虚、气阴两虚证的心率变异功率谱研究

作者	单位
陈耀青	中国中医研究院西苑医院心血管病研究室
陈可冀	中国中医研究院西苑医院心血管病研究室
孙福立	中国中医研究院老年医学研究室
涂秀华	中国中医研究院西苑医院心血管病研究室
王岩松	中国中医研究院西苑医院心血管病研究室

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中文摘要:

用心率变异功率谱观察30例气虚型、27例气阴两虚型冠心病患者的心脏植物神经调节功能,并与30名健康人进行比较,以探讨不同证型冠心病与心脏神经调节功能的关系。结果表明,气阴两虚型冠心病患者低频段功率增大,L/H 比值增高,提示其交感神经兴奋性增加;体位变化作为一种负荷试验观察不同证型冠心病的心血管神经调节反射功能。提示冠心病患者心血管压力感受性反射减退,以气阴两虚患者为著。

英文摘要:

Qi deficiency(QD)and both Qi and Yin deficiency(QYD)are most common in TCM classification of CHD patients with insufficiency syndrome.The authors used the power spectrum of spontaneous heart rate fluctuation(PSHF)to analyze the function of cardiac regulation in 30 QD patients and 27 QYD patients with CHD and compare with the control group of 30 cases for discussing the association between different TCM syndrome patterns and the function of cardiac nerve regulation. The main results were as follows:(1)Low-frequency areas of PSHF in QYD(34.15±11.60%)were significantly higher than those in QD group(26,24±11.57%)and the control group(27.80±11.65%). The L/H ratio in QYD(1.78±0.96)was significantly higher than those in QD(0.91±0.64)and the control group(0.93±0.58).The changes of PSHF in QYD could have some relations with the increasiag of the activity of sympathetic nervous system.(2)The change in body posture was used as a load test to study cardiovascular regulation in different TCM patterns of insufficiency syndrome with CHD.In control group the L/H ratio increased with the change of body posture from 0.98±0. 58 to 4.29±0.89(P<0.001),while in QD group and QYD group increased from 0.91±0.64 to 1.67±0. 83(P<0.05)and 1.78±0.96 to 1.85±0.87(P>0.2)respectively.The results suggested that cardiovas- cular baroreceptor reflex was decreased in CHD patients,and QYD group was inferior to DQ group.

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