清热利胆汤对胆病患者体内胆汁细菌的影响

作者	单位
傅华群	江西医学院第二附属医院胆病研究室
李建业	江西医学院第二附属医院胆病研究室
黄淑云	江西医学院第二附属医院微生物教研室

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中文摘要:

采用厌氧菌和需氧菌培养技术对照观察了38例胆病患者服清热利胆汤前后体内胆汁细菌的变化。发现该方能抑制胆道厌氧菌,改善胆汁多种细菌的混合感染状态。并从微生物学角度探讨了该方治疗胆道感染的机理。

英文摘要:

After’giving Qingre-Lidan Prescription to the patients with biliary diseases,the authors observed the changes of bacteria in their bile employing anaerobic and aerobic culture techniques.The results suggested that among the bile specimens from 38 patients(hepatolithiasis in 32 and biliary duct tumour in 6),the anaerobes were detected in 68.4%,aerobes in 84.2%.The mean number of the isolated bacteria from those specimens was 3.3 species.Having taken the prescription for 3～14 days (mean 6.5 days),33 cases among them recieved an operation for biliary diseases(hepatolithiasis in 32,biliary duct tumour in 1).The positive rate of anaerobes and aerobes in the bile was 42.4%,97.0% respectively.The mean of bacteria was 2.5 species.The statistical analysis showed that the positive rate of anaerobic bacteria and the mean of bacteria all had significance before and after patients taking the prescription.The above observation explored the mechanism of Qingre-Lidan Prescrip- tion used for biliary infections in microbiology.

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