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段泾云.补阳还五汤抗炎免疫药理作用[J].中国中西医结合杂志,1989,(3):164-166,134
补阳还五汤抗炎免疫药理作用
Anti-Inflammatory and Immunological Actions of Buyang Huanwu Tang
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DOI:
中文关键词:  补阳还五汤  免疫药理作用  小鼠胸腺  毛细血管通透性  抑制作用  肉芽肿  巨噬细胞吞噬功能  免疫功能  免疫器官  炎症
英文关键词:
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作者单位
段泾云 陕西省中医药研究院中药药理研究室 
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中文摘要:
      本研究证明补阳还五汤对小鼠耳壳炎症、腹腔毛细血管通透性及角叉菜胶性关节炎均有显著的对抗作用,对塑料环肉芽肿有明显的抑制作用,表明该方具有对抗渗出性炎症及增殖性炎症的作用。对免疫器官有显著增重作用,对巨噬细胞吞噬功能有明显促进作用并显著增加特异性抗体溶血紊的含量,表明该方对非特异性和特异性免疫功能均有增进作用。为文献记载该方具有"补气、活血、行瘀"之功用提供了科学依据。
英文摘要:
      Orally administered with Buyang Huanwu Tang(BHT)markedly inhibited swelling of mice’s ear induced by xylene and significantly depressed the increase of capillary permeability induced by acetic acid in mice.The carrageenin induced edema of hind paws and the proliferation of granuloma induced by subcutaneous implantation of plastic ring in rats were inhibited by BHT.The results indicated that BHT possessed a marked anti-acute and chronic inflammatory effects. The weights of spleen and thymus,and clearance rate of charcoal particles by intravenous in mice could be increased by oral administration of BHT.It markedly promoted phagocytosis of the peritoneal marcrophages of mice and hemolysin reaction.The above data revealed that anti- inflammatory effect of BHT could relatively improve immunological functions.
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