肝阳上亢证的临床研究

作者	单位
翁伟强	湖南医科大学中医基础理论研究室高血压病组
胡随瑜	湖南医科大学中医基础理论研究室高血压病组
黎杏群	湖南医科大学中医基础理论研究室高血压病组
庞伟华	湖南医科大学中医基础理论研究室高血压病组
潘其民	湖南医科大学中医基础理论研究室更年期综合征组
吴友善	湖南医科大学中医基础理论研究室更年期综合征组
向跃前	湖南医科大学中医基础理论研究室更年期综合征组
皮德仁	湖南医科大学中医基础理论研究室更年期综合征组
易振佳	湖南医科大学中医基础理论研究室更年期综合征组
林治湘	湖南医科大学中医基础理论研究室更年期综合征组
梁清华	湖南医科大学中医基础理论研究室甲状腺机能亢进组
张海男	湖南医科大学中医基础理论研究室甲状腺机能亢进组
石林阶	湖南医科大学中医基础理论研究室甲状腺机能亢进组

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中文摘要:

选择97例高血压病、更年期综合征、甲状腺机能亢进中医辨证属肝阳上亢证的患者,进行异病同治的临床研究,并与83例同样疾病的阴虚阳亢证患者对照。结果3种病总有效率依次为81.4%（降压）、100%、88.9%,其中高血压病肝阳上亢组的疗效明显高于对照组（P<0.05）。同时治疗前后检测植物神经功能、尿 MHPG-SO₄、CA、血浆环核苷酸、血浆 TXB₂与6-Keto-PGF_1a等指标,发现同证异病有类似的改变,且与疗效一致,说明这些指标对阐明肝阳上亢证本质有积极意义。

英文摘要:

In order to study the nature of Liver Yang Exuberance Syndrome（LYES）,and find new effective drug prescription to treat diseases with the syndrome,the authors chose 97 cases-with LYES of hypertension,climacteric syndrome and hyperthyroidism.A clinical study was carried out on different diseases with the syndrome including the stagnancy of Liver Qi（气）,excess of Liver Wind and rising of Liver Fire with a new prescription according to TCM theory While another 83 cases with Yin Deficiency Yang Excess Syndrome（阴虚阳亢证,YDYES）of thesame three diseases were employed as control group.The results showed that their total effective rates were 81.4%（in lowering blood pressure）,100% and 88.9% respectively.The marked effective rate of LYES of hypertension group was significantly higher than that of the control group（P<0.05）,which showed the special characteristics of the TCM syndrome.Before and after treatment,the patients with LYES of the three diseases were examined in certain laboratory tests including function of auto- nomic nervous system,urinary MHPG-SO₄,CA,plasma cAMP and TXB₂,6-keto-PGF₁α etc.The similar changes were-found in different diseases with the same syndrome.The laboratory results of the casesgot markedly improved with the improvement of their symptoms,which showed that these tests had active significance for comprehending the nature of LYES.

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