生脉散对老龄大鼠中暑的预防作用

作者	单位
林凤如	北京医院病理科
曹纯庵	北京医院病理科兰州医学院病理教研组
赵伟育	北京医院病理科兰州医学院病理教研组
顾增发	卫生部北京老年医学研究所

摘要点击次数: 1301

全文下载次数: 869

中文摘要:

选择15～18月龄 Wistar 大鼠,置于41℃高温环境中12h。其间每隔3h 向胃内灌入10%生脉散冲剂,观察生脉散预防动物中暑的效果。结果表明生脉散可降低动物死亡率,减轻心肌磷酸肌酸及 cAMP 含量的耗竭。本文还就生脉散防暑作用的某些机理进行了讨论,认为可能与该药稳定心肌能量贮备有关。结果提示生脉散对防治老年人中暑有一定应用价值。

英文摘要:

15～18 month-old Wistar rats were selected and placed in 41℃ chamber for 12 hours.10% Shen Mai San granule was poured into the stomachs every 3 hours.The preventive effects of this drug on heatstroke were observed.The result showed that the mortality of animal was decreased,the exhaustions of myocardial creatine phosphate and cAMP contents were significantly mitigated.By the view point of western medicine,the mechanisms recorded in traditional Chinese medicine about the preventive actions of this drug on heatstroke were also discussed in this study.The authors considered that the effects of Shen Mai San on"strengtheiming puhnonary Qi(气)","strengthenning Heart Qi",might be concerned in its efficiency to stabilize the energy store in myocardium,and it might be beneficial to prevent the elderly from heatstroke.

关闭