王学美,阮士怡,范英昌,乐俊曼,刘煦新,李谈,方敏,刘维,祝炳华,张军平.降脂软脉灵对成年及老龄大鼠主动脉病理形态学的影响[J].中国中西医结合杂志,1989,(11):672-674,646 |
降脂软脉灵对成年及老龄大鼠主动脉病理形态学的影响 |
The Pathological Effect of Lipld-Lowerlng and Vessel-Softening Medication on the Adult and Aged Rats |
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DOI: |
中文关键词: 大鼠主动脉 平滑肌细胞 软脉灵 主动脉内膜 病理形态学 降脂 老龄大鼠 动脉内皮 成年大鼠 主动脉弓 |
英文关键词: |
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中文摘要: |
将6月龄及15月龄的 wistar 系雄性大鼠,随机分为降脂软脉组、维生素 E组和对照组,分别喂饲降脂软脉灵,维生素 E 及正常饲料,观察对大鼠主动脉病理形态学的影响。结果表明,降脂软脉组可廷缓主动脉内膜的随龄增厚,降低内膜与中膜厚度之比,抑制平滑肌细胞的减少、胶原纤维合成及粥样斑块的形成,保护动脉内皮的完整性。 |
英文摘要: |
The Wistar’s male rats of six months and fifteen months of age were divided randomly into three groups.the Lipid-lowering and Vessel-softening medication(LVM)group,the vitamin E group and the control group.The rat aorta in-morphology was observed to study the effects of these medication.The results showed that in the LVM group,the thickening of aorta intima with age was postponed,the thickening ratio of intima to ttmica media was reduced,the reductian of smooth muscle cells was inhibited,while the synthesis of collagen fibril and the formation of plaque were also inhibited and the perfection of artery intima was protected. |
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