慢性胃炎中虚气滞证与胃粘膜幽门弯曲菌感染的病理观察

作者	单位
朱云华	江苏省中医院病理科
王黎	江苏省中医院病理科
徐景藩	江苏省中医院病理科
张梅涧	江苏省中医院内科

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中文摘要:

通过组织病理学,尿素酶试验和电镜观察,探讨不同证型的慢性胃炎与幽门弯曲菌的关系。结果表明该菌在中虚气滞组不仅检出率高(92.9%),菌量多(+++级占49.1%)侵犯部位深(达小凹底及腺腔内占73.6%),引起细胞变性崩解多(88.6%),且活动性慢性胃炎,重度炎症及中性白细胞浸润也与其他证型组问存在显著差异(P<0.05)。提示它与不同证型慢性胃炎间可能存在着病因学和组织病理学的联系。寄居上皮的超微结构变化证实了该菌的致病作用。

英文摘要:

According to the syndrome differentiation of TCM,one hundred cases of chronic gastritis were recognized as Zhongxu-Qizhi type(Group Ⅰ,57 cases)and the other types(Group Ⅱ,43 cases),the latter further divided into 36 cases of disharmony of Liver and Stomach type and 7 cases of deficiency of Stomach Yin(阴)type.The pathohistological investigation and urease test showed that the campylobacter pyloridis(CP)infected rate in the Group Ⅰ(92.9%)was very significantly higher than that in Group Ⅱ(58.1%,P<0.01);severe degree and deep location of CP infection occurred more significantly in Zhongxu-Qizhi type(52.8% and 73.6% respectively).Between the two groups,active chronic gastritis and severe invasion of polymorphonuclear cells were significantly different(P<0. 05).All these findings suggest that there were some relationships between CP infection and syndrome differentiation of TCM.

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