| 陈增潭,赵伯智,高育华,薛福珍,陈勇,苏经格,危北海,关幼波,韩纯学,于东海,王广才,毛克臣,梁永起.中药解毒养肝膏双盲法治疗慢性乙型肝炎96例临床分析[J].中国中西医结合杂志,1990,(2):71-74,67 |
| 中药解毒养肝膏双盲法治疗慢性乙型肝炎96例临床分析 |
| Clinical Study of 96 Cases with Chronic Hepatitis B Treated with Jiedu Yanggan Gao(解毒养肝膏)by a Double-Blind Method |
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| DOI： |
| 中文关键词: 解毒养肝膏 慢性乙型肝炎 双盲法 连续序贯奇偶取例 病毒复制 酸甘化阴 双向性调节 |
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| 摘要点击次数: 1801 |
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| 中文摘要: |
| 本文报道以双盲法治疗慢性乙型肝炎,观察组51例用中药复方解毒养肝膏,对照组45例用焦三仙膏。治疗后 ALT、AST、TTT 复常率观察组分别为27.3%,66.7%52.0%;对照组分别为9.1%、22.2%、44.4%。HBsAg,DNAP,HBV-DNA 阴转率观察组分别为20.0%、34.2%、31.6%;而对照组则分别为6.7%、10.8%、17.6%。总有效率观察组为74.5%,对照组为24.4%,两组差异有统计学意义。 |
| 英文摘要: |
| This paper reported 96 cases with chronic hepatitis B treated by a doable-blind method.There were 51 cases of observation group(OG) and 45 cases of control group(CG).OG was treated with Jiedu Yanggan Gao consisting of Artemisia capillaris,Taraxacum mongolicum,Plantago seed, Cephalanoplos segetum,Hedyotis diffusa,Flos Chrysanthemi Indici,Smilax glabra,Astragalus mem. branaceus,Salviae miltiorrhizae,Fructus Polygonii Orientalis,Radix Paeoniae Alba,Polygonatum sibiricum,etc.).CG was prescribed with three charred medicinal herbs (charred Fructus Crataegi, charred Fructrus Hordei Germinatus,charred fermented mixture of several medical herbs and wheat bran).The average duration of treatment was five months.All 96 cases belong to the virus- duplication-type with positive HBsAg for over one year.Among them 65.5% of cases HBeAg,DNAP and HBV-DNA were positive.20.8% of cases were positive in two out of the above tests.13 data were compared statistically between two groups,and proved to be comparable (P>0.05) before treatment.27.3% and 66.7% of cases’ALT,AST returned to normal respectively in OG after treatment.However,in CG they were 9.1% and 22.2% (P<0.05).TTT returned to normal in 52% cases of OG and 44% in CG (P>0.05).20% cases HBeAg shifted to negative in OG,but 6.7% in CG. Cases with negative DNAP in OG occupied 34.2%,but 10.8% in CG.31.6% cases’HBV-DNA changed to negative in OG,while 17.6% in CG.After comprehensive judgement,the total effective rate was 74.5% in OG and 24.4% in CG respectively (P<0.001).Eight cases were basically cured in OG and one case in CG.After one year’s follow-up,one recurred in eight patients of OG,however the only one cured in CG still relapsed. |
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